Triple-phase bone scan findings in aggressive fibromatosis. Before and after radiation therapy

• Published in: Clinical nuclear medicine Vol. 19; no. 3; p. 197
• Main Authors: Thakore, K J, Hudson, T M, Monson, D K, Scheidt, K A
• Format: Journal Article
• Language: English
• Published: United States 01.03.1994
• Subjects: Adult; Biopsy; Bone and Bones - diagnostic imaging; Bone and Bones - pathology; Bone Neoplasms - diagnostic imaging; Bone Neoplasms - secondary; Female; Fibromatosis, Abdominal - diagnostic imaging; Fibromatosis, Abdominal - pathology; Fibromatosis, Abdominal - radiotherapy; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Radionuclide Imaging; Radiotherapy Dosage; Technetium Tc 99m Medronate - analogs & derivatives; Time Factors
• ISSN: 0363-9762
• DOI: 10.1097/00003072-199403000-00006

The authors present comparative triple-phase bone scan findings in three cases of histologically proven aggressive fibromatosis both before (initial evaluation) and after radiation therapy. The purpose of the study was to compare triple-phase bone scan findings in aggressive fibromatosis both before and after radiation therapy and to determine whether any additional physiological information could be obtained. Before radiation therapy, the triple-phase bone scintigraphy demonstrated increased flow and radiotracer pooling in the areas of tumors on dynamic flow and immediate blood pool images, respectively. However, the delayed static images demonstrated variable radiotracer uptake. When compared to preradiation therapy triple-phase bone scan, decreased vascularity was well demonstrated in all three patients after radiation therapy. In addition, it also provided information regarding the changes in the size and extent of tumor, noninvaded underlying bone, and remainder of the skeleton. This additional information can be particularly useful in patients with equivocal or questionable histologic diagnosis especially from small, unrepresentative biopsies.