Cellular angiofibroma of the vulva with DNA ploidy analysis

Cellular angiofibroma (CAF) is a recently described rare soft tissue neoplasm of the vulva (with only four reported cases) that typically occurs as a well-circumscribed solid rubbery vulvar mass in middle-aged women. The distinct histologic features of bland spindle cells admixed with numerous hyali...

Full description

Saved in:
Bibliographic Details
Published inInternational journal of gynecological pathology Vol. 20; no. 2; p. 200
Main Authors Curry, J L, Olejnik, J L, Wojcik, E M
Format Journal Article
LanguageEnglish
Published United States 01.04.2001
Subjects
12E7 Antigen
Adult
Angiofibroma - diagnosis
Angiofibroma - genetics
Angiofibroma - surgery
Antigens, CD - analysis
Cell Adhesion Molecules - analysis
DNA, Neoplasm - analysis
Female
Humans
Ploidies
Vimentin - analysis
Vulvar Neoplasms - diagnosis
Vulvar Neoplasms - genetics
Vulvar Neoplasms - surgery
Online AccessGet more information

Cover

More Information
Summary:Cellular angiofibroma (CAF) is a recently described rare soft tissue neoplasm of the vulva (with only four reported cases) that typically occurs as a well-circumscribed solid rubbery vulvar mass in middle-aged women. The distinct histologic features of bland spindle cells admixed with numerous hyalinized medium to small blood vessels, and a vimentin-positive desmin-negative immunoprofile differentiates this neoplasm from other vulvar tumors such as angiomyofibroblastoma and aggressive angiomyxoma. In this report an additional case of CAF is presented with DNA ploidy analysis and CD99 immunohistochemistry.
ISSN:0277-1691
DOI:10.1097/00004347-200104000-00015