Vulvar intraepithelial neoplasia: historical aspects and current status

Vulvar intraepithelial neoplasia (VIN) is the currently accepted generic designation for the spectrum of vulvar lesions with the histologic features of squamous dysplasia and squamous cell carcinoma in situ. Although several classifications of VIN have been espoused in the past 20 years, VIN can be...

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Bibliographic Details
Published inInternational journal of gynecological pathology Vol. 20; no. 1; p. 16
Main Author Hart, W R
Format Journal Article
LanguageEnglish
Published United States 01.01.2001
Subjects
Adult
Aged
Biopsy
Bowen's Disease - history
Bowen's Disease - pathology
Carcinoma in Situ - history
Carcinoma in Situ - pathology
Carcinoma, Squamous Cell - history
Carcinoma, Squamous Cell - pathology
Female
History, 20th Century
Humans
Middle Aged
Papillomaviridae
Skin Neoplasms - history
Skin Neoplasms - pathology
Vulvar Neoplasms - history
Vulvar Neoplasms - pathology
Vulvar Neoplasms - surgery
Vulvar Neoplasms - virology
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Summary:Vulvar intraepithelial neoplasia (VIN) is the currently accepted generic designation for the spectrum of vulvar lesions with the histologic features of squamous dysplasia and squamous cell carcinoma in situ. Although several classifications of VIN have been espoused in the past 20 years, VIN can be readily classified into two principal clinicopathologic types: classic (bowenoid) VIN and simplex (differentiated) VIN. This manuscript summarizes the historical development and current status of our knowledge about VIN. Information on the clinical and pathologic aspects are detailed and illustrated, as are considerations of differential diagnosis.
ISSN:0277-1691
1538-7151
DOI:10.1097/00004347-200101000-00003