Rapid orbital lipolysis associated with critical illness and colectomy
Orbital lipolysis typically develops in the setting of a chronic catabolic state. The acute development and rapid progression of orbital lipolysis are much less commonly described. In this report, we present a rare case of a 64-year-old male who progressed from normal orbital fat content to marked o...
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Published in | Radiology case reports Vol. 16; no. 9; pp. 2347 - 2350 |
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Language | English |
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01.09.2021
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Abstract | Orbital lipolysis typically develops in the setting of a chronic catabolic state. The acute development and rapid progression of orbital lipolysis are much less commonly described. In this report, we present a rare case of a 64-year-old male who progressed from normal orbital fat content to marked orbital lipolysis in less than one month following episodes of undifferentiated shock, colonic perforation, and total colectomy. We outline the clinical course, describe the characteristic imaging findings, and provide a review of the cellular mechanisms underlying lipolysis. Our case suggests that multiple concurrent illnesses can combine to produce an extreme metabolic demand that may contribute to the uncommon development of rapidly-progressing orbital lipolysis. |
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AbstractList | Orbital lipolysis typically develops in the setting of a chronic catabolic state. The acute development and rapid progression of orbital lipolysis are much less commonly described. In this report, we present a rare case of a 64-year-old male who progressed from normal orbital fat content to marked orbital lipolysis in less than one month following episodes of undifferentiated shock, colonic perforation, and total colectomy. We outline the clinical course, describe the characteristic imaging findings, and provide a review of the cellular mechanisms underlying lipolysis. Our case suggests that multiple concurrent illnesses can combine to produce an extreme metabolic demand that may contribute to the uncommon development of rapidly-progressing orbital lipolysis. |
Author | Li, Joy Kosoy, David Umekawa, Sari Rajput, Anuj Chang, Jessica Rajput, Aikta Patel, Vishal |
Author_xml | – sequence: 1 givenname: Joy surname: Li fullname: Li, Joy organization: University of Southern California, Keck School of Medicine, Los Angeles, CA, USA – sequence: 2 givenname: Aikta surname: Rajput fullname: Rajput, Aikta organization: St. George's University, University Centre, Grenada – sequence: 3 givenname: David surname: Kosoy fullname: Kosoy, David organization: St. George's University, University Centre, Grenada – sequence: 4 givenname: Sari surname: Umekawa fullname: Umekawa, Sari organization: The Queen's Medical Center, Department of Pulmonary Critical Care, Honolulu, HI, USA – sequence: 5 givenname: Anuj surname: Rajput fullname: Rajput, Anuj organization: Los Angeles Imaging and Interventional Consultants at PIH Health, Department of Radiology, Whittier, CA, USA – sequence: 6 givenname: Jessica surname: Chang fullname: Chang, Jessica organization: University of Southern California, Keck School of Medicine, Department of Ophthalmology, Los Angeles, CA, USA – sequence: 7 givenname: Vishal surname: Patel fullname: Patel, Vishal email: vishal.patel@med.usc.edu organization: University of Southern California, Keck School of Medicine, Department of Radiology, Los Angeles, CA, USA |
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Keywords | Enophthalmos Cachexia Catabolism Orbital lipolysis |
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Title | Rapid orbital lipolysis associated with critical illness and colectomy |
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