Rapid orbital lipolysis associated with critical illness and colectomy

Orbital lipolysis typically develops in the setting of a chronic catabolic state. The acute development and rapid progression of orbital lipolysis are much less commonly described. In this report, we present a rare case of a 64-year-old male who progressed from normal orbital fat content to marked o...

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Published inRadiology case reports Vol. 16; no. 9; pp. 2347 - 2350
Main Authors Li, Joy, Rajput, Aikta, Kosoy, David, Umekawa, Sari, Rajput, Anuj, Chang, Jessica, Patel, Vishal
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.09.2021
Elsevier
Subjects
Cachexia
Case Report
Catabolism
Enophthalmos
Orbital lipolysis
Enophthalmos
Cachexia
Catabolism
Orbital lipolysis
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Summary:Orbital lipolysis typically develops in the setting of a chronic catabolic state. The acute development and rapid progression of orbital lipolysis are much less commonly described. In this report, we present a rare case of a 64-year-old male who progressed from normal orbital fat content to marked orbital lipolysis in less than one month following episodes of undifferentiated shock, colonic perforation, and total colectomy. We outline the clinical course, describe the characteristic imaging findings, and provide a review of the cellular mechanisms underlying lipolysis. Our case suggests that multiple concurrent illnesses can combine to produce an extreme metabolic demand that may contribute to the uncommon development of rapidly-progressing orbital lipolysis.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2021.06.001