Multifocal precursor B-cell lymphoblastic lymphoma in an infant with cardiac involvement: A case report

• Published in: Radiology case reports Vol. 16; no. 8; pp. 2043 - 2046
• Main Authors: Ninh, Tran Phan, Duc, Nguyen Minh, Trung, Nguyen Ngoc, Duc, Le Anh, Ngoc, Doan-Van, My, Thieu-Thi Tra, Sang, Nguyen-Van, Thong, Pham Minh
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.08.2021; Elsevier
• Subjects: Case Report; Heart tumor; Infant; Lymphoma; Multimodality imaging; Right atrium; Infant; Heart tumor; Multimodality imaging; Lymphoma; Right atrium
• ISSN: 1930-0433; 1930-0433
• DOI: 10.1016/j.radcr.2021.04.080

Lymphoma with cardiac involvement is a high-risk lesion, especially in children. We report a rare clinical case of multifocal precursor B-cell lymphoblastic lymphoma in a child with cardiac involvement. A 4-year-old boy presented to the Vietnam National Children's Hospital with a vague headache, but magnetic resonance imaging of the head was normal. After 1 week, the patient showed symptoms of chest pain, fatigue, dyspnea, and abdominal pain. On transthoracic echocardiography and multislice computed tomography of the thorax, a mass was detected in the right atrial wall. Abdominal ultrasound showed a small bowel intussusception, multiple nodules in the intestinal wall, and mesenteric lymph nodes. Histopathology of the bowel confirmed the diagnosis of multifocal precursor B-cell lymphoblastic lymphoma. The patient responded to 3 cycles of chemotherapy for lymphoma. Therefore, combining multiple imaging methods allowed for early diagnosis and improved treatment.