Pre-exposure prophylaxis for South African adolescents: What evidence?

Adolescents and young women, particularly in South Africa, are at increased risk of HIV acquisition. To date, we have had limited primary prevention options to offer. Oral pre-exposure prophylaxis (PrEP) is an additional prevention modality that has now been proven to reduce HIV acquisition in those...

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Bibliographic Details
Published inSouth African medical journal Vol. 105; no. 11; pp. 907 - 911
Main Authors Bekker, L-G, Gill, K, Wallace, M
Format Journal Article
LanguageEnglish
Published South Africa Health & Medical Publishing Group 01.11.2015
Subjects
Administration, Oral
Adolescent
Anti-HIV Agents - therapeutic use
Female
HIV infection in children
HIV Infections - epidemiology
HIV Infections - prevention & control
Humans
Male
Pre-Exposure Prophylaxis
Prevention
South Africa - epidemiology
South Africa
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Summary:Adolescents and young women, particularly in South Africa, are at increased risk of HIV acquisition. To date, we have had limited primary prevention options to offer. Oral pre-exposure prophylaxis (PrEP) is an additional prevention modality that has now been proven to reduce HIV acquisition in those who take it consistently during periods of HIV infection exposure. We review the PrEP evidence in adolescents and highlight some of the research gaps. Our recommendation is to increase the number of demonstration projects and other scale-up opportunities to offer oral PrEP to at-risk adolescents, and monitor carefully to answer the outstanding questions.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0256-9574
DOI:10.7196/SAMJ.2015.v105i11.10222