Prevalence and antimicrobial sensitivity pattern in urinary tract infection in febrile under-5s at a children's emergency unit in Nigeria

• Published in: Annals of tropical paediatrics Vol. 23; no. 1; pp. 39 - 45
• Main Authors: Musa-Aisien, A. S., Ibadin, O. M., Ukoh, G., Akpede, G. O.
• Format: Journal Article
• Language: English
• Published: Leeds Taylor & Francis 01.03.2003; Maney
• Subjects: Bacterial diseases; Bacterial diseases of the urinary system; Biological and medical sciences; Blood Cell Count; Child, Preschool; Drug Resistance, Bacterial; Emergencies; Escherichia coli - isolation & purification; Female; Fever - complications; Fever - drug therapy; Fever - epidemiology; Human bacterial diseases; Humans; Infant; Infant, Newborn; Infectious diseases; Klebsiella pneumoniae - isolation & purification; Male; Medical sciences; Nephrology. Urinary tract diseases; Nigeria - epidemiology; Prevalence; Sex Ratio; Staphylococcus aureus - isolation & purification; Tropical medicine; Urinary system involvement in other diseases. Miscellaneous; Urinary Tract Infections - complications; Urinary Tract Infections - drug therapy; Urinary Tract Infections - epidemiology; Urinary tract. Prostate gland; Nigeria; Africa; Human; Resistance; Sensitivity; Urinary system disease; Prevalence; Urinary tract disease; Epidemiology; Child; Antimicrobial agent; Fever
• ISSN: 0272-4936; 1465-3281
• DOI: 10.1179/000349803125002850

The prevalence of urinary tract infection (UTI) in 300 consecutively admitted, febrile, preschool children with and without a focus of infection was evaluated to determine the contribution of UTI to febrile illnesses. Uncentrifuged urine was evaluated by culture and microscopy. The prevalence of UTI was 9% and was significantly higher in girls than in boys. It was also significantly higher when urine infection had been clinically suspected than in those with other diagnoses. Temperature >41°C and abdominal pain were significantly associated with UTI. Other features significantly associated with UTI were fever of at least 7 days duration, a peak evaluation temperature ≥38.3°C and a white blood cell count >10/mm 3 . Escherichia coli, Klebsiella pneumonia and Staphylococcus aureus were the only organisms isolated and they all showed high in vitro sensitivity to clavulanic acid-potentiated amoxycillin, gentamicin and ceftriaxone but were poorly sensitive to co-trimoxazole.