Evaluation of Mechanical and Thermal Properties of Hydroxyapatite-levan Composite Bone Graft
Biodegradable materials have been received great attention as bone graft substitutes for bone regeneration and tissue engineering. However, their low mechanical property remains a major challenge for the use in load-bearing applications. Here, we developed mechanically reinforced composite scaffold...
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| Published in | Biotechnology and bioprocess engineering Vol. 26; no. 2; pp. 201 - 207 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Seoul
The Korean Society for Biotechnology and Bioengineering
01.04.2021
Springer Nature B.V 한국생물공학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1226-8372 1976-3816 |
| DOI | 10.1007/s12257-020-0094-6 |
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| Abstract | Biodegradable materials have been received great attention as bone graft substitutes for bone regeneration and tissue engineering. However, their low mechanical property remains a major challenge for the use in load-bearing applications. Here, we developed mechanically reinforced composite scaffold containing adhesive levan as a binder for sintered hydroxyapatite (sHAp) and then examined the mechanical and thermal properties of the composite scaffold. We found that sHAp-levan composite scaffold exhibited remarkably enhanced mechanical strength, which is similar to that of polymethyl methacrylate (PMMA) bone cement. This composite scaffold can be utilized as a promising bone graft for bone regeneration and tissue engineering. |
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| AbstractList | Biodegradable materials have been received great attention as bone graft substitutes for bone regeneration and tissue engineering. However, their low mechanical property remains a major challenge for the use in loadbearing applications. Here, we developed mechanically reinforced composite scaffold containing adhesive levan as a binder for sintered hydroxyapatite (sHAp) and then examined the mechanical and thermal properties of the composite scaffold. We found that sHAp-levan composite scaffold exhibited remarkably enhanced mechanical strength, which is similar to that of polymethyl methacrylate (PMMA) bone cement. This composite scaffold can be utilized as a promising bone graft for bone regeneration and tissue engineering. KCI Citation Count: 0 Biodegradable materials have been received great attention as bone graft substitutes for bone regeneration and tissue engineering. However, their low mechanical property remains a major challenge for the use in load-bearing applications. Here, we developed mechanically reinforced composite scaffold containing adhesive levan as a binder for sintered hydroxyapatite (sHAp) and then examined the mechanical and thermal properties of the composite scaffold. We found that sHAp-levan composite scaffold exhibited remarkably enhanced mechanical strength, which is similar to that of polymethyl methacrylate (PMMA) bone cement. This composite scaffold can be utilized as a promising bone graft for bone regeneration and tissue engineering. |
| Author | Joo, Kye Song, Younghoon Seo, Jeong Hyun |
| Author_xml | – sequence: 1 givenname: Younghoon surname: Song fullname: Song, Younghoon organization: School of Chemical Engineering, Yeungnam University – sequence: 2 givenname: Kye surname: Joo fullname: Joo, Kye email: kijoo@ewha.ac.kr organization: Division of Chemical Engineering and Materials Science, Ewha Womans University – sequence: 3 givenname: Jeong Hyun surname: Seo fullname: Seo, Jeong Hyun email: jhseo78@yu.ac.kr organization: School of Chemical Engineering, Yeungnam University |
| BackLink | https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002716162$$DAccess content in National Research Foundation of Korea (NRF) |
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| CitedBy_id | crossref_primary_10_3390_molecules28145407 crossref_primary_10_1016_j_jmbbm_2023_106229 crossref_primary_10_1016_j_bioactmat_2024_04_006 crossref_primary_10_1021_acs_biomac_4c01264 crossref_primary_10_1007_s11814_023_1396_0 crossref_primary_10_1016_j_polymer_2024_127523 crossref_primary_10_1016_j_carbpol_2025_123337 crossref_primary_10_1016_j_ijbiomac_2021_07_036 crossref_primary_10_1016_j_carpta_2024_100482 crossref_primary_10_1007_s12257_022_0286_3 crossref_primary_10_1007_s12257_023_0043_2 crossref_primary_10_1007_s12257_024_00025_5 |
| Cites_doi | 10.1186/1741-7015-9-66 10.1063/1.4769987 10.1016/j.cap.2011.05.011 10.1016/j.bioactmat.2017.05.007 10.1016/S0142-9612(01)00331-3 10.3390/ma11101813 10.1088/1758-5082/6/3/035010 10.1016/j.ijbiomac.2004.01.002 10.1007/s10856-015-5406-6 10.1146/annurev.matsci.28.1.271 10.1016/j.biomaterials.2003.12.005 10.1002/bit.21648 10.1016/j.polymer.2003.10.009 10.1016/j.msea.2006.05.158 10.22203/eCM.v011a06 10.1007/BF00123370 10.1016/j.biomaterials.2005.05.058 10.1002/jbm.b.30774 10.1007/s10973-011-1877-y 10.1016/B978-1-78242-033-0.00010-9 10.1016/j.compscitech.2013.11.006 10.1016/j.progpolymsci.2010.01.006 10.1016/j.fct.2011.11.016 10.1016/j.biomaterials.2006.01.039 10.5312/wjo.v4.i2.67 10.1016/j.ceramint.2018.02.156 10.5772/8148 |
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| References | Wang, Yeung (CR3) 2017; 2 Mehar, Mahapatra, Patel (CR24) 2015; 3 Puppi, Chiellini, Piras, Chiellini (CR4) 2010; 35 Wolff, Salikov, Antonyuk, Heinrich, Schneider (CR23) 2014; 90 CR30 Wang, Wang, Marois, Guidoin, Zhang (CR6) 2005; 26 Arora, Chan, Gupta, Diwan (CR22) 2013; 4 Prokopiev, Sevostianov (CR10) 2006; 431 Axente, Sima, Sima, Erginer, Eroglu, Serban, Ristoscu, Petrescu, Toksoy Oner, Mihailescu (CR20) 2014; 6 Yoo, Yoon, Cha, Lee (CR19) 2004; 34 Pandharipande, Sondawale (CR15) 2016; 5 Tõnsuaadu, Gross, Plūduma, Veiderma (CR26) 2012; 110 Wei, Ma (CR12) 2004; 25 Wei, Chen, Yu (CR29) 2003; 44 Weiner, Wagner (CR1) 1998; 28 Liu, Mucalo (CR14) 2015 Elashmawi, Baieth (CR28) 2012; 12 Dimitriou, Jones, McGonagle, Giannoudis (CR2) 2011; 9 Rezwan, Chen, Blaker, Boccaccini (CR5) 2006; 27 Siddiqui, Pickering, Mucalo (CR9) 2018; 11 Stea, Visentin, Savarino, Donati, Pizzoferrato, Moroni, Caja (CR11) 1995; 6 Sima, Axente, Sima, Tuyel, Eroglu, Serban, Ristoscu, Petrescu, Toksoy Oner, Mihailescu (CR21) 2012; 101 Anandan, Jaiswal (CR27) 2018; 44 Liu, Luo, Ye, Zeng (CR18) 2012; 50 Santos, Clarke, Braden, Guitian, Davy (CR25) 2002; 23 Vamze, Pilmane, Skagers (CR7) 2015; 26 Zhao, Zhang, Ning, Guo, Xu (CR8) 2007; 83 Fu, Nie, Ho, Wang, Wang (CR13) 2008; 99 Kim, Chung, Kim, Kim, Han, Kim (CR17) 2006; 56 Wahl, Czernuszka (CR16) 2006; 11 S H Yoo (94_CR19) 2004; 34 K Tõnsuaadu (94_CR26) 2012; 110 D Wahl (94_CR16) 2006; 11 S Weiner (94_CR1) 1998; 28 H A Siddiqui (94_CR9) 2018; 11 C L Wei (94_CR29) 2003; 44 I S Elashmawi (94_CR28) 2012; 12 S Stea (94_CR11) 1995; 6 E Axente (94_CR20) 2014; 6 M Arora (94_CR22) 2013; 4 K H Kim (94_CR17) 2006; 56 O Prokopiev (94_CR10) 2006; 431 M F H Wolff (94_CR23) 2014; 90 R Dimitriou (94_CR2) 2011; 9 W Wang (94_CR3) 2017; 2 J Vamze (94_CR7) 2015; 26 F Sima (94_CR21) 2012; 101 K Rezwan (94_CR5) 2006; 27 Z Wang (94_CR6) 2005; 26 C Santos (94_CR25) 2002; 23 J Liu (94_CR18) 2012; 50 G Wei (94_CR12) 2004; 25 Y C Fu (94_CR13) 2008; 99 94_CR30 A Mehar (94_CR24) 2015; 3 S L Pandharipande (94_CR15) 2016; 5 D Puppi (94_CR4) 2010; 35 C Liu (94_CR14) 2015 D Anandan (94_CR27) 2018; 44 Y Zhao (94_CR8) 2007; 83 |
| References_xml | – volume: 5 start-page: 3410 year: 2016 end-page: 3416 ident: CR15 article-title: Review on synthesis of hydroxyapatite and its bio-composites publication-title: Int. J. Sci. Eng. Technol. Res. – volume: 3 start-page: 594 year: 2015 end-page: 604 ident: CR24 article-title: Assessment of mechanical properties and wear behaviour of ceramic composites publication-title: Int. J. Eng. Technol. Manage. Appl. Sci. – ident: CR30 – volume: 9 start-page: 66 year: 2011 ident: CR2 article-title: Bone regeneration: current concepts and future directions publication-title: BMC Med. doi: 10.1186/1741-7015-9-66 – volume: 101 start-page: 233705 year: 2012 ident: CR21 article-title: Combinatorial matrix-assisted pulsed laser evaporation: Single-step synthesis of biopolymer compositional gradient thin film assemblies publication-title: Appl. Phys. Lett. doi: 10.1063/1.4769987 – volume: 12 start-page: 141 year: 2012 end-page: 146 ident: CR28 article-title: Spectroscopic studies of hydroxyapatite in PVP/PVA polymeric matrix as biomaterial publication-title: Curr. Appl. Phys. doi: 10.1016/j.cap.2011.05.011 – volume: 2 start-page: 224 year: 2017 end-page: 247 ident: CR3 article-title: Bone grafts and biomaterials substitutes for bone defect repair: A review publication-title: Bioact. Mater. doi: 10.1016/j.bioactmat.2017.05.007 – volume: 23 start-page: 1897 year: 2002 end-page: 1904 ident: CR25 article-title: Water absorption characteristics of dental composites incorporating hydroxyapatite filler publication-title: Biomaterials. doi: 10.1016/S0142-9612(01)00331-3 – volume: 11 start-page: 1813 year: 2018 ident: CR9 article-title: A review on the use of hydroxyapatite-carbonaceous structure composites in bone replacement materials for strengthening purposes publication-title: Materials. doi: 10.3390/ma11101813 – volume: 6 start-page: 035010 year: 2014 ident: CR20 article-title: Combinatorial MAPLE gradient thin film assemblies signalling to human osteoblasts publication-title: Biofabrication. doi: 10.1088/1758-5082/6/3/035010 – volume: 34 start-page: 37 year: 2004 end-page: 41 ident: CR19 article-title: Antitumor activity of levan polysaccharides from selected microorganisms publication-title: Int. J. Biol. Macromol. doi: 10.1016/j.ijbiomac.2004.01.002 – volume: 26 start-page: 73 year: 2015 ident: CR7 article-title: Biocompatibility of pure and mixed hydroxyapatite and α-tricalcium phosphate implanted in rabbit bone publication-title: J. Mater. Sci. Mater. Med. doi: 10.1007/s10856-015-5406-6 – volume: 28 start-page: 271 year: 1998 end-page: 298 ident: CR1 article-title: The material bone: structure-mechanical function relations publication-title: Ann. Rev. Mater. Sci. doi: 10.1146/annurev.matsci.28.1.271 – volume: 25 start-page: 4749 year: 2004 end-page: 4757 ident: CR12 article-title: Structure and properties of nano-hydroxyapatite/polymer composite scaffolds for bone tissue engineering publication-title: Biomaterials. doi: 10.1016/j.biomaterials.2003.12.005 – volume: 99 start-page: 996 year: 2008 end-page: 1006 ident: CR13 article-title: Optimized bone regeneration based on sustained release from three-dimensional fibrous PLGA/HAp composite scaffolds loaded with BMP-2 publication-title: Biotechnol. Bioeng. doi: 10.1002/bit.21648 – volume: 44 start-page: 8185 year: 2003 end-page: 8193 ident: CR29 article-title: Temperature modulated DSC and DSC studies on the origin of double melting peaks in poly(ether ether ketone) publication-title: Polymer. doi: 10.1016/j.polymer.2003.10.009 – volume: 431 start-page: 218 year: 2006 end-page: 227 ident: CR10 article-title: Dependence of the mechanical properties of sintered hydroxyapatite on the sintering temperature publication-title: Mat. Sci. Eng. A. doi: 10.1016/j.msea.2006.05.158 – volume: 11 start-page: 43 year: 2006 end-page: 56 ident: CR16 article-title: Collagen-hydroxyapatite composites for hard tissue repair publication-title: Eur. Cells. Mater. doi: 10.22203/eCM.v011a06 – volume: 56 start-page: 395 year: 2006 end-page: 406 ident: CR17 article-title: Cosmeceutical properties of levan produced by Zymomonas mobilis publication-title: J. Cosmet. Sci. – volume: 6 start-page: 455 year: 1995 end-page: 459 ident: CR11 article-title: Quantitative analysis of the bone-hydroxyapatite coating interface publication-title: J. Mater. Sci. Mater. Med. doi: 10.1007/BF00123370 – volume: 26 start-page: 7387 year: 2005 end-page: 7401 ident: CR6 article-title: Evaluation of biodegradable synthetic scaffold coated on arterial prostheses implanted in rat subcutaneous tissue publication-title: Biomaterials. doi: 10.1016/j.biomaterials.2005.05.058 – volume: 83 start-page: 121 year: 2007 end-page: 126 ident: CR8 article-title: Synthesis and cellular biocompatibility of two kinds of HAP with different nanocrystal morphology publication-title: J. Biomed Mater. Res. B Appl. Biomater. doi: 10.1002/jbm.b.30774 – volume: 110 start-page: 647 year: 2012 end-page: 659 ident: CR26 article-title: A review on the thermal stability of calcium apatites publication-title: J. Therm. Anal. Calorim. doi: 10.1007/s10973-011-1877-y – start-page: 211 year: 2015 end-page: 234 ident: CR14 article-title: Collagen-hydroxyapatite composite scaffolds for tissue engineering publication-title: Hydroxyapatite (Hap) for Biomedical Applications. doi: 10.1016/B978-1-78242-033-0.00010-9 – volume: 90 start-page: 154 year: 2014 end-page: 159 ident: CR23 article-title: Novel, highly-filled ceramic-polymer composites synthesized by a spouted bed spray granulation process publication-title: Compos. Sci. Technol. doi: 10.1016/j.compscitech.2013.11.006 – volume: 35 start-page: 403 year: 2010 end-page: 440 ident: CR4 article-title: Polymeric materials for bone and cartilage repair publication-title: Prog. Polym. Sci. doi: 10.1016/j.progpolymsci.2010.01.006 – volume: 50 start-page: 767 year: 2012 end-page: 772 ident: CR18 article-title: Preparation, antioxidant and antitumor activities of different derivatives of levan from endophytic bacterium EJS-3 publication-title: Food. Chem. Toxicol. doi: 10.1016/j.fct.2011.11.016 – volume: 27 start-page: 3413 year: 2006 end-page: 3431 ident: CR5 article-title: Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering publication-title: Biomaterials. doi: 10.1016/j.biomaterials.2006.01.039 – volume: 4 start-page: 67 year: 2013 end-page: 74 ident: CR22 article-title: Polymethylmethacrylate bone cements and additives: A review of the literature publication-title: World J. Orthop. doi: 10.5312/wjo.v4.i2.67 – volume: 44 start-page: 9401 year: 2018 end-page: 9407 ident: CR27 article-title: Synthesis and characterization of human bone-like hydroxyapatite using Schiff’s base publication-title: Ceram. Int. doi: 10.1016/j.ceramint.2018.02.156 – volume: 25 start-page: 4749 year: 2004 ident: 94_CR12 publication-title: Biomaterials. doi: 10.1016/j.biomaterials.2003.12.005 – volume: 99 start-page: 996 year: 2008 ident: 94_CR13 publication-title: Biotechnol. Bioeng. doi: 10.1002/bit.21648 – volume: 28 start-page: 271 year: 1998 ident: 94_CR1 publication-title: Ann. Rev. Mater. Sci. doi: 10.1146/annurev.matsci.28.1.271 – volume: 6 start-page: 035010 year: 2014 ident: 94_CR20 publication-title: Biofabrication. doi: 10.1088/1758-5082/6/3/035010 – volume: 35 start-page: 403 year: 2010 ident: 94_CR4 publication-title: Prog. Polym. Sci. doi: 10.1016/j.progpolymsci.2010.01.006 – volume: 2 start-page: 224 year: 2017 ident: 94_CR3 publication-title: Bioact. Mater. doi: 10.1016/j.bioactmat.2017.05.007 – volume: 4 start-page: 67 year: 2013 ident: 94_CR22 publication-title: World J. Orthop. doi: 10.5312/wjo.v4.i2.67 – volume: 12 start-page: 141 year: 2012 ident: 94_CR28 publication-title: Curr. Appl. Phys. doi: 10.1016/j.cap.2011.05.011 – volume: 44 start-page: 8185 year: 2003 ident: 94_CR29 publication-title: Polymer. doi: 10.1016/j.polymer.2003.10.009 – volume: 9 start-page: 66 year: 2011 ident: 94_CR2 publication-title: BMC Med. doi: 10.1186/1741-7015-9-66 – volume: 11 start-page: 43 year: 2006 ident: 94_CR16 publication-title: Eur. Cells. Mater. doi: 10.22203/eCM.v011a06 – volume: 83 start-page: 121 year: 2007 ident: 94_CR8 publication-title: J. Biomed Mater. Res. B Appl. Biomater. doi: 10.1002/jbm.b.30774 – volume: 50 start-page: 767 year: 2012 ident: 94_CR18 publication-title: Food. Chem. Toxicol. doi: 10.1016/j.fct.2011.11.016 – ident: 94_CR30 doi: 10.5772/8148 – volume: 110 start-page: 647 year: 2012 ident: 94_CR26 publication-title: J. Therm. Anal. Calorim. doi: 10.1007/s10973-011-1877-y – volume: 34 start-page: 37 year: 2004 ident: 94_CR19 publication-title: Int. J. Biol. Macromol. doi: 10.1016/j.ijbiomac.2004.01.002 – volume: 431 start-page: 218 year: 2006 ident: 94_CR10 publication-title: Mat. Sci. Eng. A. doi: 10.1016/j.msea.2006.05.158 – volume: 101 start-page: 233705 year: 2012 ident: 94_CR21 publication-title: Appl. Phys. Lett. doi: 10.1063/1.4769987 – volume: 23 start-page: 1897 year: 2002 ident: 94_CR25 publication-title: Biomaterials. doi: 10.1016/S0142-9612(01)00331-3 – volume: 3 start-page: 594 year: 2015 ident: 94_CR24 publication-title: Int. J. Eng. Technol. Manage. Appl. Sci. – volume: 27 start-page: 3413 year: 2006 ident: 94_CR5 publication-title: Biomaterials. doi: 10.1016/j.biomaterials.2006.01.039 – start-page: 211 volume-title: Hydroxyapatite (Hap) for Biomedical Applications. year: 2015 ident: 94_CR14 doi: 10.1016/B978-1-78242-033-0.00010-9 – volume: 6 start-page: 455 year: 1995 ident: 94_CR11 publication-title: J. Mater. Sci. Mater. Med. doi: 10.1007/BF00123370 – volume: 56 start-page: 395 year: 2006 ident: 94_CR17 publication-title: J. Cosmet. Sci. – volume: 11 start-page: 1813 year: 2018 ident: 94_CR9 publication-title: Materials. doi: 10.3390/ma11101813 – volume: 26 start-page: 73 year: 2015 ident: 94_CR7 publication-title: J. Mater. Sci. Mater. Med. doi: 10.1007/s10856-015-5406-6 – volume: 26 start-page: 7387 year: 2005 ident: 94_CR6 publication-title: Biomaterials. doi: 10.1016/j.biomaterials.2005.05.058 – volume: 5 start-page: 3410 year: 2016 ident: 94_CR15 publication-title: Int. J. Sci. Eng. Technol. Res. – volume: 90 start-page: 154 year: 2014 ident: 94_CR23 publication-title: Compos. Sci. Technol. doi: 10.1016/j.compscitech.2013.11.006 – volume: 44 start-page: 9401 year: 2018 ident: 94_CR27 publication-title: Ceram. Int. doi: 10.1016/j.ceramint.2018.02.156 |
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| SubjectTerms | Adhesives Biodegradability Biodegradable materials Biodegradation Biomedical materials Biotechnology Bone cements Bone grafts Bone growth Bone implants bone transplantation Cement Chemistry Chemistry and Materials Science Composite materials Grafting Grafts Hydroxyapatite Industrial and Production Engineering Levan Mechanical properties Polymethyl methacrylate Polymethylmethacrylate Regeneration Regeneration (physiology) Research Paper Scaffolds Skin & tissue grafts strength (mechanics) Substitute bone Thermal properties Thermodynamic properties Tissue engineering 생물공학 |
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| Title | Evaluation of Mechanical and Thermal Properties of Hydroxyapatite-levan Composite Bone Graft |
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