Study of mitochondrial swelling, membrane fluidity and ROS production induced by nano-TiO2 and prevented by Fe incorporation

• Published in: Toxicology research (Cambridge) Vol. 8; no. 5; pp. 711 - 722
• Main Authors: Barkhade, Tejal, Mahapatra, Santosh Kumar, Banerjee, Indrani
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 01.09.2019
• Subjects: Animal tissues; Anisotropy; Biocompatibility; Chemistry; Fluidity; Iron; Membrane fluidity; Mitochondria; Morphology; Nanoparticles; Poultry; Succinate dehydrogenase; Swelling; Titanium dioxide; Toxicity; Viscosity

Abstract The potential impact of TiO2 and Fe incorporated TiO2 nanoparticles at the organelle level has been reported. The toxicity of the samples on mitochondria isolated from chicken liver tissue has been examined through mitochondrial swelling, membrane fluidity, ROS generation capacity, and acti...