Simulation of the growth of neurospheres
Under appropriate conditions, the neural stem cells are able to proliferate and to form suspended neurospheres containing stem cells and neuronal and glial progenitors in different stages of differentiation. Our lattice Monte Carlo simulations, taking into account the effect of spatial constraints a...
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Published in | Europhysics letters Vol. 68; no. 1; pp. 134 - 140 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
IOP Publishing
01.10.2004
EDP Sciences |
Subjects | |
Online Access | Get full text |
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Summary: | Under appropriate conditions, the neural stem cells are able to proliferate and to form suspended neurospheres containing stem cells and neuronal and glial progenitors in different stages of differentiation. Our lattice Monte Carlo simulations, taking into account the effect of spatial constraints and cell-cell adhesion on cell diffusion and division, show that i) the neurosphere-size distribution is very broad and ii) the spatial distribution of various cells inside neurospheres is heterogeneous. |
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Bibliography: | istex:B8E9049D4834EF02B17B3BA07FB60241AA84A9E3 ark:/67375/80W-LJPDG073-X publisher-ID:epl8384 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
ISSN: | 0295-5075 1286-4854 |
DOI: | 10.1209/epl/i2004-10170-1 |