Cavernosal alpha-blockade: a new technique for investigating and treating erectile impotence

Intravacernosal injection of phenoxybenzamine, in a dose too small to have significant general effects, caused full erection lasting between half an hour and 30 hours in 30 of 4 potent men (2 normal, 2 anorgasmic) and in 6 of 11 impotent men. In the remaining potent man and 3 of the remaining eleven...

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Bibliographic Details
Published inBritish journal of psychiatry Vol. 143; p. 332
Main Author Brindley, G S
Format Journal Article
LanguageEnglish
Published England 01.10.1983
Subjects
Adult
Erectile Dysfunction - drug therapy
Humans
Injections
Male
Middle Aged
Penis
Phenoxybenzamine - administration & dosage
Phentolamine - administration & dosage
Time Factors
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Summary:Intravacernosal injection of phenoxybenzamine, in a dose too small to have significant general effects, caused full erection lasting between half an hour and 30 hours in 30 of 4 potent men (2 normal, 2 anorgasmic) and in 6 of 11 impotent men. In the remaining potent man and 3 of the remaining eleven impotent men have had sexual intercourse, for the first time for months or years, while under the drug. The practical implications of this new discovery are discussed.
ISSN:0007-1250
DOI:10.1192/bjp.143.4.332