An Integrated Potentiostat With an Electrochemical Cell Using Thin-Film Transistors

• Published in: IEEE transactions on electron devices Vol. 56; no. 9; pp. 2114 - 2119
• Main Authors: Kimura, M., Fukushima, H., Sagawa, Y., Setsu, K., Hara, H., Inoue, S.
• Format: Journal Article
• Language: English
• Published: New York, NY IEEE 01.09.2009; Institute of Electrical and Electronics Engineers; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Amplifiers; Applied sciences; Biosensors; Circuit properties; CMOS integrated circuits; Electric, optical and optoelectronic circuits; Electrical measurements; Electrochemical analysis; Electrochemical cells; Electrodes; Electronic circuits; Electronics; Exact sciences and technology; Glass; Glucose; Glucose oxidase; integrated potentiostat; micrototal analysis system ( mu -TAS); poly-Si; Potentiostats; Semiconductor devices; Semiconductor electronics. Microelectronics. Optoelectronics. Solid state devices; Sugar; Thin film transistors; thin-film transistors (TFTs); Transistors; Electrochemical analysis; Operational amplifier; Microsensor; Polycrystal; Electrochemical cell; thin-film transistors (TFTs); Cyclic voltammetry; Electrochemical properties; Thin film transistor; poly-Si; Diagnostic aid; integrated potentiostat; Medical application; Wafer; micrototal analysis system (μ-TAS)
• ISSN: 0018-9383; 1557-9646
• DOI: 10.1109/TED.2009.2026120

We developed an integrated potentiostat with an electrochemical cell using thin-film transistors (TFTs). The integrated potentiostat consisted of three operational amplifiers composed of poly-Si TFTs, whereas the electrochemical cell was fabricated using a printing technology. These microsensor components were integrated on a glass wafer to assemble a micrototal analysis system. A cyclic-voltammetry measurement was performed as a standard biosensing experiment to confirm the elementary function of the integrated potentiostat. The expected characteristic was acquired by an amperometric enzymatic redox reaction using glucose oxidase and ferrocene mediators, and a glucose concentration of as low as 0.7 mM was detected, which is sufficient sensitivity for some medical applications including diabetic diagnosis.