Microwave-Assisted Synthesis of Substituted 2-(2H-Chromen-3-yl)-5-phenyl-1H-imidazole Based Coumarin Derivatives and Their Antimicrobial Activity

A number of new imidazole-coumarin structures have been synthesised under conventional heating and MW irradiation methods. Structures of all synthesized compounds are characterized by IR, NMR and Mass spectra. The title compounds have been tested for their antimicrobial activity against bacteria Bac...

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Bibliographic Details
Published inRussian journal of general chemistry Vol. 91; no. 4; pp. 711 - 716
Main Authors Ashok, D., Ramakrishna, Katta, Nagaraju, Nalaparaju, Reddy, M. Ram, Dharavath, Ravinder, Sarasija, M.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.04.2021
Springer Nature
Springer
Springer Nature B.V
Subjects
Antifungal agents
Antiinfectives and antibacterials
Antimicrobial agents
Chemistry
Chemistry and Materials Science
Chemistry, Multidisciplinary
Chemistry/Food Science
Coliforms
Coumarin
Coumarins
E coli
Fusarium oxysporum
Imidazole
Klebsiella
Mass spectra
NMR
Nuclear magnetic resonance
Physical Sciences
Science & Technology
microwave irradiation
antimicrobial activity
imidazole
coumarins
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Summary:A number of new imidazole-coumarin structures have been synthesised under conventional heating and MW irradiation methods. Structures of all synthesized compounds are characterized by IR, NMR and Mass spectra. The title compounds have been tested for their antimicrobial activity against bacteria Bacillus subtilis , Staphylococcus aureus , Escherichia coli , and Klebsiella pneumonia as well as fungi Aspergillus Niger , Aspergillus flavus , and Fusarium oxysporum . Several products have exhibited antimicrobial activity against all organisms.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363221040216