A clinical review of outcomes of the Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder (MTA)

• Published in: Current psychiatry reports Vol. 10; no. 5; pp. 424 - 431
• Main Authors: Murray, Desiree W., Arnold, L. Eugene, Swanson, Jim, Wells, Karen, Burns, Karen, Jensen, Peter, Hechtman, Lily, Paykina, Natalya, Legato, Lauren, Strauss, Tara
• Format: Journal Article
• Language: English
• Published: New York Current Science Inc 01.10.2008; Springer Nature B.V
• Subjects: Achievement; Adolescent; Attention Deficit and Disruptive Behavior Disorders - epidemiology; Attention Deficit and Disruptive Behavior Disorders - rehabilitation; Attention Deficit Disorder with Hyperactivity - epidemiology; Attention Deficit Disorder with Hyperactivity - rehabilitation; Attention deficit hyperactivity disorder; Behavior Therapy; Central Nervous System Stimulants - adverse effects; Central Nervous System Stimulants - therapeutic use; Child; Child, Preschool; Combined Modality Therapy; Community Mental Health Services; Comorbidity; Follow-Up Studies; Humans; Hyperactivity; Juvenile Delinquency - rehabilitation; Juvenile Delinquency - statistics & numerical data; Medicine; Medicine & Public Health; Psychiatry; Social Adjustment; Socialization; Substance-Related Disorders - epidemiology; Substance-Related Disorders - rehabilitation; Treatment Outcome; Stimulant Medication; Multimodal Treatment Study; Shire Pharmaceutical; Acad Child Adolesc Psychiatry; Clin Child Psychol
• ISSN: 1523-3812; 1535-1645
• DOI: 10.1007/s11920-008-0068-4

Over the past decade, the Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder has provided a bewildering wealth of data (more than 70 peer-reviewed articles) addressing treatment-related questions for children with attention-deficit/hyperactivity disorder. However, the take-home messages for clinicians may not always be clear. Therefore, this article reviews key findings, including relative benefits of medication and behavioral treatments, longterm effects at 2 and 3 years, treatment mediators and moderators, preliminary delinquency and substance use outcomes, and growth suppression related to stimulant use. Appropriate interpretations of the findings and their limitations are discussed, and recommendations for clinical practice are derived.