Quantitative Characterization of Concentrated Cell Pellet Biophantoms using Statistical Models for the Ultrasound Echo Envelope

Statistical analysis is performed on the envelopes of ultrasonic backscattered signals from concentrated human leukemia cell pellet biophantoms. Two statistical distributions (Nakagami and Homodyned-K) are used to assess scatterer concentration. Seven concentrations ranging from 0.006 to 0.30 (corre...

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Bibliographic Details
Published inPhysics procedia Vol. 70; pp. 1091 - 1095
Main Authors Cristea, A., Franceschini, E., Lin, F., Mamou, J., Cachard, C., Basset, O.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 2015
Subjects
cell pellet biophantoms
concentrated media
Homodyned-K distribution
Nakagami distribution
Tissue Characterization
Nakagami distribution
Homodyned-K distribution
Tissue Characterization
concentrated media
cell pellet biophantoms
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Summary:Statistical analysis is performed on the envelopes of ultrasonic backscattered signals from concentrated human leukemia cell pellet biophantoms. Two statistical distributions (Nakagami and Homodyned-K) are used to assess scatterer concentration. Seven concentrations ranging from 0.006 to 0.30 (corresponding to 3 to 250 scatterers per resolution cell at 25 and 35MHz) are considered. The values of the Nakagami parameter m increase with the number of scatterers per resolution cell but plateaus around 1 for concentrations greater than 0.03, while the Homodyned-K parameter α continued to increase and does not plateau, even if the estimation is less precise.
ISSN:1875-3892
1875-3892
DOI:10.1016/j.phpro.2015.08.233