Approaches in topical ocular drug delivery and developments in the use of contact lenses as drug-delivery devices

Drug-delivery approaches have diversified over the last two decades with the emergence of nanotechnologies, smart polymeric systems and multimodal functionalities. The intended target for specific treatment of disease is the key defining developing parameter. One such area which has undergone signif...

Full description

Saved in:
Bibliographic Details
Published inTherapeutic delivery Vol. 8; no. 7; pp. 521 - 541
Main Authors Mehta, Prina, Haj-Ahmad, Rita, Al-Kinani, Ali, Arshad, Muhammad Sohail, Chang, Ming-Wei, Alany, Raid G, Ahmad, Zeeshan
Format Journal Article
LanguageEnglish
Published England Future Science Ltd 01.07.2017
Subjects
Administration, Ophthalmic
Contact Lenses
Drug Delivery Systems
drug loading
emulsions
Eye
Humans
hydrogel
matrix composition
nanotechnology
ocular drug delivery
Polymers
theranostic
drug loading
emulsions
hydrogel
matrix composition
nanotechnology
ocular drug delivery
theranostic
contact lenses
Online AccessGet full text

Cover

More Information
Summary:Drug-delivery approaches have diversified over the last two decades with the emergence of nanotechnologies, smart polymeric systems and multimodal functionalities. The intended target for specific treatment of disease is the key defining developing parameter. One such area which has undergone significant advancements relates to ocular delivery. This has been expedited by the development of material advancement, mechanistic concepts and through the deployment of advanced process technologies. This review will focus on the developments within lens-based drug delivery while touching on conventional and current methods of topical ocular drug delivery. A summary table will provide quick reference to note the key findings in this area. In addition, the review also elucidates current theranostic and diagnostic approaches based on ocular lenses.
ISSN:2041-5990
2041-6008
DOI:10.4155/tde-2017-0018