Preoperative Abnormal P and QTc Dispersion Intervals in Patients with Metabolic Syndrome

• Published in: Anesthesia and analgesia Vol. 112; no. 4; pp. 824 - 827
• Main Authors: HANCI, Volkan, YURTLU, Serhan, AYDIN, Mustafa, BILIR, Serhat, ERDOGAN, Gülay, OKYAY, Rahşan Dilek, AYOGLU, Hilal, TURAN, Isil Özkocak
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.04.2011
• Subjects: Adult; Anesthesia; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Arrhythmias, Cardiac - complications; Arrhythmias, Cardiac - physiopathology; Biological and medical sciences; Electrocardiography - methods; Female; Heart Conduction System - physiology; Heart Rate - physiology; Humans; Male; Medical sciences; Metabolic Syndrome - complications; Metabolic Syndrome - physiopathology; Metabolic Syndrome - surgery; Middle Aged; Preoperative Care - methods; Prospective Studies; Retrospective Studies; Endocrinopathy; Human; Metabolic diseases; Cardiovascular disease; Anesthesia; Preoperative; Metabolic syndrome
• ISSN: 0003-2999; 1526-7598
• DOI: 10.1213/ANE.0b013e3181f68ff8

We evaluated P wave dispersion (Pwd), QT, corrected QT (QTc), QT dispersion, and corrected QT dispersion (QTcd) intervals in patients with metabolic syndrome (MetS). Patients scheduled to undergo elective noncardiac surgery were included in the study. The main diagnoses, anthropometric measurements, waist circumferences, body mass index, electrocardiograms, serum levels of electrolytes, glucose, and lipids were recorded for all patients. QTc, QTcd intervals were determined with the Bazett formula. MetS (group M, n = 36) was diagnosed using the Adult Treatment Panel III. Controls (group C, n = 40) were chosen on the basis of patients with no MetS and matched for age and gender. There were no differences between groups in terms of age, sex, or serum electrolyte levels (P > 0.05). Waist circumferences, body mass index, serum glucose, and triglyceride values in group M were significantly higher than those in group C (P < 0.001). In group M, Pwd, QTc, QT dispersion and QTcd intervals were significantly longer than those in group C (P < 0.001). This finding and our retrospective analysis suggest that these patients may be at greater risk of perioperative arrhythmias.