Photodynamic therapy in superficial bladder cancer: past, present and future

For many reasons, such as toxicity and lack of selectivity of photosensitisers, as well as complexity of technical procedures and inconstant therapeutic results, photodynamic therapy of highly recurrent superficial bladder cancer never gained wide acceptance in the urological community. However, the...

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Bibliographic Details
Published inUrolithiasis Vol. 29; no. 6; pp. 396 - 405
Main Authors Jichlinski, P, Leisinger, H J
Format Journal Article
LanguageEnglish
Published Germany Springer Nature B.V 01.12.2001
Subjects
Bladder cancer
Cancer
Humans
Photochemotherapy - trends
Photodynamic therapy
Urinary Bladder Neoplasms - drug therapy
Urinary Bladder Neoplasms - physiopathology
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Summary:For many reasons, such as toxicity and lack of selectivity of photosensitisers, as well as complexity of technical procedures and inconstant therapeutic results, photodynamic therapy of highly recurrent superficial bladder cancer never gained wide acceptance in the urological community. However, the 25 years of experience combined with the recent discovery of new photosensitisers, such as protoporphyrin IX (PpIX) induced by 5-aminolevulinic acid (ALA) or ALA-derivatives or hypericin open new, very interesting perspectives in this therapeutic field.
ISSN:0300-5623
2194-7228
1434-0879
2194-7236
DOI:10.1007/s002400100215