plotsr: visualizing structural similarities and rearrangements between multiple genomes

• Published in: Bioinformatics Vol. 38; no. 10; pp. 2922 - 2926
• Main Authors: Goel, Manish, Schneeberger, Korbinian
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 13.05.2022
• ISSN: 1367-4803; 1367-4811; 1460-2059; 1367-4811
• DOI: 10.1093/bioinformatics/btac196

Abstract Summary Third-generation genome sequencing technologies have led to a sharp increase in the number of high-quality genome assemblies. This allows the comparison of multiple assembled genomes of individual species and demands new tools for visualizing their structural properties. Here, we present plotsr, an efficient tool to visualize structural similarities and rearrangements between genomes. It can be used to compare genomes on chromosome level or to zoom in on any selected region. In addition, plotsr can augment the visualization with regional identifiers (e.g. genes or genomic markers) or histogram tracks for continuous features (e.g. GC content or polymorphism density). Availability and implementation plotsr is implemented as a python package and uses the standard matplotlib library for plotting. It is freely available under the MIT license at GitHub (https://github.com/schneebergerlab/plotsr) and bioconda (https://anaconda.org/bioconda/plotsr). Supplementary information Supplementary data are available at Bioinformatics online.