The toxicity of Capparis tomentosa in goats

Eleven Nubian goats were given daily oral doses ranging from 0·05 to 5 g per kg per day of the dried leaves of Capparis tomentosa and died or were killed in extremis at various times after dosing. The main signs of poisoning were inappetence, muscular weakness, incoordination of movement, pain in th...

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Bibliographic Details
Published inJournal of comparative pathology Vol. 90; no. 2; pp. 187 - 195
Main Authors Ahmed, O.M.M., Adam, S.E.I.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.01.1980
Subjects
Animals
Aspartate Aminotransferases - blood
Erythrocyte Count
Goats
Kidney - pathology
Liver - pathology
Plant Poisoning - blood
Plant Poisoning - pathology
Plant Poisoning - veterinary
poisonous plants
Sudan
Sudan
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Summary:Eleven Nubian goats were given daily oral doses ranging from 0·05 to 5 g per kg per day of the dried leaves of Capparis tomentosa and died or were killed in extremis at various times after dosing. The main signs of poisoning were inappetence, muscular weakness, incoordination of movement, pain in the sacral region, dragging of the hind limbs, pallor of the visible mucous membranes and recumbency. An increase in the activity of GOT, in the concentrations of ammonia, sodium and potassium and a decrease in total protein and calcium were detected in the serum. Haematological changes indicated the development of hypochromic erythrocytopaenia. The out-standing pathological changes were perineuronal spaces in the grey matter of the spinal cord, centrilobular hepatocellular necrosis and degeneration or necrosis of the cells of the renal convoluted tubules.
ISSN:0021-9975
1532-3129
DOI:10.1016/0021-9975(80)90055-9