Effect of angiotensin II on vascular resistance in whole-body perfused dogfish

1. 1. The effect of angiotensin II (AII), norepinephrine (NE), epinephrine (E) and isoproterenol (ISO) was observed on the branchial and systemic circulations in a whole-body-pump perfused dogfish preparation. 2. 2. NE and E increased systemic blood flow resistance, but decreased branchial resistanc...

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Published inComparative biochemistry and physiology. C, Comparative pharmacology Vol. 73; no. 1; pp. 45 - 49
Main Authors Opdyke, D.F., Wilde, D.W., Holcombe, R.F.
Format Journal Article
LanguageEnglish
Published England Elsevier B.V 1982
Subjects
Angiotensin II - pharmacology
Animals
Dogfish - physiology
Epinephrine - pharmacology
Isoproterenol - pharmacology
Norepinephrine - pharmacology
Regional Blood Flow - drug effects
Sharks - physiology
Squalus acanthias
Vascular Resistance - drug effects
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Summary:1. 1. The effect of angiotensin II (AII), norepinephrine (NE), epinephrine (E) and isoproterenol (ISO) was observed on the branchial and systemic circulations in a whole-body-pump perfused dogfish preparation. 2. 2. NE and E increased systemic blood flow resistance, but decreased branchial resistance. 3. 3. ISO decreased both systematic and branchial blood flow resistance. 4. 4. AII had no significant effect on either branchial or systemic resistance.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0306-4492
DOI:10.1016/0306-4492(82)90166-6