Biodegradable Thermogel as Culture Matrix of Bone Marrow Mesenchymal Stem Cells for Potential Cartilage Tissue Engineering

• Published in: Chinese journal of polymer science Vol. 32; no. 12; pp. 1590 - 1601
• Main Authors: Zhang, Yan-bo, Ding, Jian-xun, Xu, Wei-guo, Wu, Jie, Chang, Fei, Zhuang, Xiu-li, Chen, Xue-si, Wang, Jin-cheng
• Format: Journal Article
• Language: English
• Published: Heidelberg Chinese Chemical Society and Institute of Chemistry, CAS 01.12.2014
• Subjects: Bone marrow; Cartilage; Cellular; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Condensed Matter Physics; Degradation; Hydrogels; Industrial Chemistry/Chemical Engineering; Polymer Sciences; Polymerization; Stem cells; Tissue engineering; 三嵌段共聚物; 两亲共聚物; 可生物降解; 培养基质; 大分子引发剂; 热凝胶; 软骨组织工程; 骨髓间充质干细胞; Scaffold; Thermogel; Bone marrow mesenchymal stem cell; Cartilage defect repair

Poly（lactide-co-glycolide）-poly（ethylene glycol）-poly（lactide-co-glycolide）（PLGA-PEG-PLGA） triblock copolymer was synthesized through the ring-opening polymerization of LA and GA with PEG as macroinitiator and stannous octoate as catalyst. The amphiphilic copolymer self-assembled into micelles in aq...