Design and Synthesis of Pyrano[2,3-a]carbazoles by Multicomponent Reaction

A facile, efficient, three-component reaction of 2,3,4,9-tetrahydro-1H-carbazol-1-one, malononitrile, and aromatic/heteroaromatic aldehydes in dimethylformamide (DMF) gave pyrano[2,3-a]carbazoles in good yields, at reflux condition, using a catalytic amount of piperidine.

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Bibliographic Details
Published inSynthetic communications Vol. 45; no. 5; pp. 586 - 598
Main Authors Murali, Karunanidhi, Arya, Kripalaya Ratheesh, Prasad, Karnam Jayarampillai Rajendra
Format Journal Article
LanguageEnglish
Published PHILADELPHIA Taylor & Francis 04.03.2015
Taylor & Francis Ltd
Subjects
Aldehydes
Chemistry
Chemistry, Organic
malononitrile
multicomponent reaction
Physical Sciences
piperidine
pyrano[2,3-a]carbazoles
Science & Technology
malononitrile
piperidine
CARBAZOLE ALKALOIDS
pyrano[2,3-a]carbazoles
Aldehydes
multicomponent reaction
DERIVATIVES
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Summary:A facile, efficient, three-component reaction of 2,3,4,9-tetrahydro-1H-carbazol-1-one, malononitrile, and aromatic/heteroaromatic aldehydes in dimethylformamide (DMF) gave pyrano[2,3-a]carbazoles in good yields, at reflux condition, using a catalytic amount of piperidine.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397911.2014.956368