Combined use of beta-tricalcium phosphate with different porosities can accelerate bone remodelling in open-wedge high tibial osteotomy

• Published in: Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology Vol. 29; pp. 30 - 34
• Main Authors: Sasaki, Sota, Maeyama, Akira, Kiyama, Takahiko, Kamada, Satoshi, Kobayashi, Tomohiro, Ishii, Satohiro, Yamamoto, Takuaki
• Format: Journal Article
• Language: English
• Published: Asia-Pacific Knee, Arthroscopy and Sports Medicine Society 01.07.2022; Elsevier
• Subjects: Beta-tricalcium phosphate; Bone remodelling; Original; Osteotomy; Porosity
• ISSN: 2214-6873; 2214-6873
• DOI: 10.1016/j.asmart.2022.05.004

Background/ObjectiveBeta-tricalcium phosphate (β-TCP) is often used as a gap filler in open-wedge high tibial osteotomy (OWHTO). The aim of the present study was to investigate the effects of using β-TCP with different porosities on bone remodelling after OWHTO.Methods: We evaluated 29 knees in 26 patients that underwent OWHTO using β-TCP with porosities of 60% and 75% (combined group). A further 30 knees in 28 patients that underwent OWHTO using β-TCP with 60% porosity alone were allocated as a control group. In the combined group, a β-TCP block with 75% porosity was inserted into the gap at the cancellous bone site and a β-TCP block with 60% porosity was inserted into the medial cortical bone side. In the control group, a β-TCP block with 60% porosity was inserted into the osteotomy gap. The bone remodelling phases of the inserted β-TCP blocks were evaluated on standard anteroposterior radiographs using the modified van Hemert classification at 3 and 6 months post-operatively. ResultsThe rate of satisfactory bone remodelling at the cancellous bone sites was 86.2% (25/29) in the combined group and 0% (0/30) in the control group at 3 months post-operatively (p<0.05), progressing to 96.6% (28/29) in the combined group and 20% (6/30) in the control group at 6 months post-operatively (p<0.05). ConclusionThe present study demonstrated that combined use of β-TCP with high and low porosities can significantly enhance bone formation. The combined use of artificial bones with different porosities is useful for early bone remodelling in OWHTO.