Non-coding RNAs in Saccharomyces cerevisiae: what is the function?

New sequencing technologies and high-resolution microarray analysis have revealed genome-wide pervasive transcription in many eukaryotes, generating a large number of RNAs with no coding capacity. The focus of current debate is whether many of these ncRNAs (non-coding RNAs) are functional, and if so...

Full description

Saved in:
Bibliographic Details
Published inBiochemical Society transactions Vol. 40; no. 4; p. 907
Main Authors Wu, Jian, Delneri, Daniela, O'Keefe, Raymond T
Format Journal Article
LanguageEnglish
Published England 01.08.2012
Subjects
Gene Expression Regulation - genetics
Gene Expression Regulation - physiology
RNA, Untranslated - genetics
Saccharomyces cerevisiae - genetics
Transcription, Genetic - genetics
Online AccessGet more information

Cover

More Information
Summary:New sequencing technologies and high-resolution microarray analysis have revealed genome-wide pervasive transcription in many eukaryotes, generating a large number of RNAs with no coding capacity. The focus of current debate is whether many of these ncRNAs (non-coding RNAs) are functional, and if so, what their function is. In this review, we describe recent discoveries in the field of ncRNAs in the yeast Saccharomyces cerevisiae. Newly identified ncRNAs in this budding yeast, their functions in gene regulation and possible mechanisms of action are discussed.
ISSN:1470-8752
DOI:10.1042/BST20120042