Channel current analysis estimates the pore-formation and the penetration of transmembrane peptides

We measured the current signal of the transmembrane model peptides using the barrel-stave, toroidal pore, and penetration models in order to establish a precise assignment of the channel signals. In addition, we analyzed the spike signals to estimate the membrane penetration of model cell-penetratio...

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Bibliographic Details
Published inAnalyst (London) Vol. 143; no. 15; pp. 3540 - 3543
Main Authors Sekiya, Yusuke, Sakashita, Shungo, Shimizu, Keisuke, Usui, Kenji, Kawano, Ryuji
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 23.07.2018
Subjects
Animals
Antimicrobial Cationic Peptides - chemistry
Lipid Bilayers - chemistry
Membrane Proteins - chemistry
Penetration
Peptides
Peptides - chemistry
Pore formation
Protein Conformation
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Xenopus Proteins - chemistry
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Summary:We measured the current signal of the transmembrane model peptides using the barrel-stave, toroidal pore, and penetration models in order to establish a precise assignment of the channel signals. In addition, we analyzed the spike signals to estimate the membrane penetration of model cell-penetration peptides of different lengths.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0003-2654
1364-5528
DOI:10.1039/c8an00243f