Changing trends in the management of phaeochromocytoma
Background The recent experience of a specialist endocrine surgery unit in the management of phaeochromocytoma is reviewed. Methods Over a 14‐year period (June 1978 to June 1992) 43 patients (14 men, 29 women) with a mean age of 42 years were referred with phaeochromocytoma. Results Biochemical conf...
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Published in | British journal of surgery Vol. 85; no. 1; pp. 117 - 120 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Science Ltd
01.01.1998
Wiley |
Subjects | |
Online Access | Get full text |
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Summary: | Background
The recent experience of a specialist endocrine surgery unit in the management of phaeochromocytoma is reviewed.
Methods
Over a 14‐year period (June 1978 to June 1992) 43 patients (14 men, 29 women) with a mean age of 42 years were referred with phaeochromocytoma.
Results
Biochemical confirmation was usually by measurement of 24‐h urinary vallinylmandelic acid. From 1980 venous sampling was replaced by computed tomography as the primary localizing procedure. 131I‐meta‐iodobenzylguanidine scintigraphy was used in all patients between 1984 and 1987, but selectively after that. With regard to the operative approach used, between 1978 and 1983 midline or flank incisions were used, and from 1984 to 1992 subcostal or posterior approaches were used predominantly. There was one operative (30‐day) death. One patient died 24 months after operation from recurrent malignant phaeochromocytoma, and three patients died during follow‐up from unrelated causes. The remaining patients (mean follow‐up 30 months) have no evidence of recurrent phaeochromocytoma, although four remain on antihypertensive medication.
Conclusion
Improved imaging of phaeochromocytoma obviates the need for transperitoneal exploration, allowing selected phaeochromocytomas to be successfully managed using an extraperitoneal approach. © 1998 British Journal of Surgery Society Ltd |
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Bibliography: | ArticleID:BJS380 istex:12D37197D38E1D9BC04D9B84C7DB2738B37D77B1 ark:/67375/WNG-6TH0K7B3-D ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0007-1323 1365-2168 |
DOI: | 10.1046/j.1365-2168.1998.02875.x |