Electrospun xanthan gum-chitosan nanofibers as delivery carrier of hydrophobic bioactives
•Electrospinning of viscoelastic gels of xanthan gum-chitosan.•Production of stable electrospun xanthan-chitosan nanofibers in aqueous media.•Novel carrier for the encapsulation and controlled release of hydrophobic bioactives. Viscoelastic gels of xanthan gum-chitosan(X-Ch) in formic acid were elec...
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Published in | Materials letters Vol. 228; pp. 322 - 326 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Amsterdam
Elsevier B.V
01.10.2018
Elsevier BV |
Subjects | |
Online Access | Get full text |
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Summary: | •Electrospinning of viscoelastic gels of xanthan gum-chitosan.•Production of stable electrospun xanthan-chitosan nanofibers in aqueous media.•Novel carrier for the encapsulation and controlled release of hydrophobic bioactives.
Viscoelastic gels of xanthan gum-chitosan(X-Ch) in formic acid were electrospun to produce nanofibers, stable in aqueous media, for the encapsulation and release of curcumin (Cu). After 120 h, the nanofibers released lower amount of curcumin (∼20%) at pH 2.2 comparatively to the release in neutral media (∼50%), suggesting that X-Ch nanofibers could be used as a carrier for the encapsulation of hydrophobic bioactive compounds with long-term pH-stimulated release properties. |
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ISSN: | 0167-577X 1873-4979 |
DOI: | 10.1016/j.matlet.2018.06.033 |