Wearable chem-biosensing devices: from basic research to commercial market
Wearable chem-biosensors have been garnering tremendous interest due to the significant potential in tailored healthcare diagnostics and therapeutics. With the development of the medical diagnostics revolution, wearable chem-biosensors as a rapidly emerging wave allow individuals to perform on-deman...
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| Published in | Lab on a chip Vol. 21; no. 22; pp. 4285 - 431 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
Cambridge
Royal Society of Chemistry
09.11.2021
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1473-0197 1473-0189 1473-0189 |
| DOI | 10.1039/d1lc00438g |
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| Summary: | Wearable chem-biosensors have been garnering tremendous interest due to the significant potential in tailored healthcare diagnostics and therapeutics. With the development of the medical diagnostics revolution, wearable chem-biosensors as a rapidly emerging wave allow individuals to perform on-demand detection and obtain the required in-depth information. In contrast to commercial wearables, which tend to be miniaturized for measuring physical activities, the recent progressive wearable chem-biosensing device have mainly focused on non-invasive or minimally invasive monitoring biomarkers at the molecular level. Wearables is a multidisciplinary subject, and chem-biosensing is one of the most significant technologies. In this review, the currently basic academic research of wearable chem-biosensing devices and its commercial transformation were summarized and highlighted. Moreover, some representative wearable products on the market for individual health managements are presented. Strategies for the identification and sensing of biomarkers are discussed to further promote the development of wearable chem-biosensing devices. We also shared the limitations and breakthroughs of the next generation of chemo-biosensor wearables, from home use to clinical diagnosis.
This review aims to help readers engage in wearable fundamental research or wearables commercial market by evaluating the biosensing performance. |
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| Bibliography: | Dr. Xingyu Jiang is a Chair Professor at the Southern University of Science and Technology, Shenzhen, China. He obtained his Ph.D. at Harvard University (Chemistry, 2004). His research interests include microfluidics and nanomedicine and their applications in diagnostics, screening for therapeutics, as well as engineered tissues. He was awarded the National Science Foundation of China's Distinguished Young Scholars Award, the Scopus Young Researcher Gold Award, and the Human Frontier Science Program Young Investigator Award. He is a Fellow of the Royal Society of Chemistry (UK) and American Institute of Medical and Biological Engineering. Dr. Xueen Fang is currently a full Associate Professor in the Chemistry Department at Fudan University. He received his Ph.D. in Analytical Chemistry from Fudan University. He was awarded the Shanghai Pujiang Talent and Shanghai Excellent Technology Leader. He finished his postdoctoral program in Chemical Biology in The Hong Kong University of Science and Technology. His research interests mainly focus on nucleic acid amplification, biosensing technique, fully integrated microfluidics system, and point-of-care testing for the molecular diagnosis of diseases. Dr. Bin Yang is currently a postdoctoral research fellow in the Chemistry Department at Fudan University. He received his Ph.D. in Analytical Chemistry from Fudan University in 2020. He was awarded the China National Postdoctoral Innovative Talents and Shanghai Post-doctoral Excellence. His current research focuses on wearable biosensors and microneedles patch for cancer-derived cell-free DNA capture and analysis. Dr. Jilie Kong is currently a full Professor in Analytical Chemistry at Fudan University and a group leader of the Engineering Research Center for Innovative Scientific Instrument, Fudan University. He received his Ph.D. in Analytical Chemistry from Fudan University. He was awarded the National Science Foundation of China's Distinguished Young Scholars Award. His research areas mainly focus on biosensors, micro-nano biochemical analysis, microanalysis instruments, and new methods and techniques for molecular diagnosis of diseases. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 |
| ISSN: | 1473-0197 1473-0189 1473-0189 |
| DOI: | 10.1039/d1lc00438g |