A heteromultivalent host-guest sensor array for cell recognition and discrimination

We present a supramolecular sensor array based on a series of heteromultivalent macrocyclic coassemblies using amphiphilic calixarenes and cyclodextrin as the building blocks for cell recognition. The corresponding cross-reactivity between the coassemblies and cells served as the unique fingerprint...

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 58; no. 95; pp. 13198 - 1321
Main Authors Hu, Xin-Yue, Hu, Zong-Ying, Tian, Jia-Hong, Shi, Lin, Ding, Fei, Li, Hua-Bin, Guo, Dong-Sheng
Format Journal Article
LanguageEnglish
Published Cambridge Royal Society of Chemistry 29.11.2022
Subjects
Calixarenes
Cyclodextrins
Recognition
Sensor arrays
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Summary:We present a supramolecular sensor array based on a series of heteromultivalent macrocyclic coassemblies using amphiphilic calixarenes and cyclodextrin as the building blocks for cell recognition. The corresponding cross-reactivity between the coassemblies and cells served as the unique fingerprint for cell classification, and successfully identified the normal cell lines, cancerous cell lines, and cross-contaminated cells. Supramolecular heteromultivalent sensor arrays were constructed by coassembling different amphiphilic calixarenes and cyclodextrin, and applied in cell identification.
Bibliography:Electronic supplementary information (ESI) available. See DOI
https://doi.org/10.1039/d2cc04963e
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ISSN:1359-7345
1364-548X
1364-548X
DOI:10.1039/d2cc04963e