Lifestyle determinants as predictor of severity of metabolic associated fatty liver disease (MAFLD)

• Published in: Egyptian Liver Journal Vol. 13; no. 1; pp. 47 - 10
• Main Authors: Attia, Abeer, Labib, Nargis Albert, Abdelzaher, Noha Essameldin Elsayed, Musa, Sherief, Atef, Mira
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 19.09.2023; Springer Nature B.V; SpringerOpen
• Subjects: Abdomen; Cholangitis; Diabetes; Epidemiology; Exercise; Family medical history; Food; Food frequency questionnaire; Hepatitis; Hepatology; Hypertension; Lifestyle; Lifestyles; Liver cancer; Liver diseases; MAFLD; Medicine; Medicine & Public Health; Metabolism; Microbiology; Nutrition; Original Research Article; Pathology; Physical activity; Physical fitness; Pittsburg sleep quality index; Questionnaires; Sleep disorders; Sociodemographics; Ultrasonic imaging; Variables; Virology; MAFLD; Pittsburg sleep quality index; Lifestyle; Food frequency questionnaire; Physical activity
• ISSN: 2090-6218; 2090-6226
• DOI: 10.1186/s43066-023-00282-8

Background Metabolic-associated fatty liver disease (MAFLD) is a public health issue that can result in liver cirrhosis and its complications. Aim of work Assess the dietary pattern, physical activity, and sleep quality of MAFLD patients. Methods Cross-sectional study of 77 MAFLD patients being present in the outpatient clinic of Endemic Medicine Department at Cairo University Hospital. An interview questionnaire including sociodemographic, medical history, validated food frequency questionnaire (FFQ), Pittsburg Sleep Quality Index (PSQI), and international physical activity questionnaire (IPAQ) were utilized to collect data. Results Among patients, 36%, 34%, and 30% had liver steatosis grades I (mild), II (moderate), and III (severe) respectively. Waist circumference, body mass index (BMI), daily caloric and carbohydrate intake, impaired sleep quality, and low physical activity were significantly linked with steatosis grades. The independent significant predictors for MAFLD severity were waist circumference ( P  = 0.011, OR 1.119), poor sleep quality ( P  = 0.038, OR 3.871), habitual sleep efficiency (OR 3.402, 95%CI 1.403–8.252), daytime dysfunction (OR 2.487, 95%CI 1.374–4.501), and physical activity ( P  = 0.027, OR 4.6). Conclusion Waist circumference, poor sleep quality, habitual sleep efficiency, daytime dysfunction, and low physical activity were the real marked predictors for MAFLD severity.