Age-dependent changes in hypothalamic catecholamine turnover rate following castration in Turkeys

Catecholamine (CA) turnover rates were determined in 6- and 10-week-old turkeys following castration. Dopamine (DA) turnover rates decreased while norepinephrine (NE) and epinephrine (E) turnover rates increased in 10-week-old, but not in 6-week-old, turkeys. The changes in CA turnover rates were ac...

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Bibliographic Details
Published inGeneral and comparative endocrinology Vol. 42; no. 3; pp. 290 - 296
Main Authors El Halawani, M.E., Burke, W.H., Ogren, L.A.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.01.1980
Subjects
Aging
Animals
Castration
Catecholamines - metabolism
Dopamine - metabolism
Epinephrine - metabolism
Gonadotropin-Releasing Hormone - blood
Hypothalamus - drug effects
Hypothalamus - metabolism
Luteinizing Hormone - blood
Male
Methyltyrosines - pharmacology
Norepinephrine - metabolism
Radioimmunoassay - methods
Turkeys - physiology
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Summary:Catecholamine (CA) turnover rates were determined in 6- and 10-week-old turkeys following castration. Dopamine (DA) turnover rates decreased while norepinephrine (NE) and epinephrine (E) turnover rates increased in 10-week-old, but not in 6-week-old, turkeys. The changes in CA turnover rates were accompanied by an enhanced release of LH. Administration of an inhibitor of CA synthesis, α-methyltyrosine (MT), reduced the LH rise that follows castration. The results provide additional evidence for the involvement of catecholaminergic mechanisms in LH release.
Bibliography:L
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ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:0016-6480
1095-6840
DOI:10.1016/0016-6480(80)90157-4