In Vivo Triple Quantum Filtered Twisted Projection Sodium MRI of Human Articular Cartilage

In this work, we present the first triple quantum filtered (TQF) sodium MR images of the human knee joint in vivo. A 3D TQF data set of 16 slices was obtained in 20 min using a TQF pulse sequence preencoded to a twisted projection imaging readout. Images clearly demarcate patellar cartilage and also...

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Published inJournal of magnetic resonance (1997) Vol. 141; no. 2; pp. 286 - 290
Main Authors Borthakur, Arijitt, Hancu, Ileana, Boada, Fernando E., Shen, Gary X., Shapiro, Erik M., Reddy, Ravinder
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.12.1999
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Summary:In this work, we present the first triple quantum filtered (TQF) sodium MR images of the human knee joint in vivo. A 3D TQF data set of 16 slices was obtained in 20 min using a TQF pulse sequence preencoded to a twisted projection imaging readout. Images clearly demarcate patellar cartilage and also demonstrate fluid signal suppressed by the triple quantum filter. Biexponential transverse relaxation times were calculated by fitting the TQF free induction decay to a theoretical signal expression. The average values from three healthy volunteers were T2fall* = 9.59 ± 0.35 ms and T2rise* = 0.84 ± 0.06 ms. Application of TQF imaging in biological tissues is discussed.
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content type line 23
ISSN:1090-7807
1096-0856
DOI:10.1006/jmre.1999.1923