Ultrasound Assessment of Intima-media Thickness and Diameter of Carotid Arteries in Patients Undergoing Hemodialysis or Renal Transplantation

• Published in: Current medical science Vol. 38; no. 4; pp. 727 - 733
• Main Authors: Li, Zhao-jun, Du, Lian-fang, Qin, Yan, Liu, Ji-bin, Luo, Xiang-hong
• Format: Journal Article
• Language: English
• Published: Wuhan Huazhong University of Science and Technology 01.08.2018; Department of Ultrasound, Shanghai General Hospital,Shanghai Jiao Tong University, Shanghai 200080, China%Department of Urology, Shanghai General Hospital,Shanghai Jiao Tong University, Shanghai 200080, China%Department of Radiology, Thomas Jefferson University, Philadelphia 19107, USA%Department of Echocardiography, Shanghai General Hospital,Shanghai Jiao Tong University, Shanghai 200080, China
• Subjects: Medicine; Medicine & Public Health; arteriosclerosis; ultrasonic radiofrequency tracking; carotid intima-media thickness; renal transplantation; age
• ISSN: 2096-5230; 2523-899X; 1672-0733; 2523-899X
• DOI: 10.1007/s11596-018-1937-7

Summary Renal transplant (RT) recipients have a high risk of developing cardiovascular diseases. However, the effects of renal transplantation on the development of arteriosclerosis have been controversial. The carotid intima-media thickness (СШТ) and diameter (CD) are important indicators of vascular remodeling and arteriosclerosis. In this study, 31 patients with hemodialysis (HD), 31 RT recipients and 84 age- and gender-matched control subjects were enrolled. Their CIMT and CD were measured by ultrasonic radiofrequency tracking, and the linear regression models and Z test were used to identify the progression of arteriosclerosis and the risk factors. Compared with HD group, RT group had significantly lower CIMT and CD. CIMT was found to be associated with age, body weight, resistance index and diastolic velocity, while CD was associated significantly with age, body weight, pulsatility index, end diastolic velocity and diastolic blood pressure (DBP), respectively. The correlation curves between CIMT and age showed the slopes of curves were decreased successively in control, RT and HD groups, and the curves between CD and age showed the slopes were decreased in order of RT > control > HD groups. It was concluded that CIMT and CD were significantly correlated with age in RT and moderately with age in HD patients. RT could reduce the progress of arteriosclerosis in patients with end-stage renal disease.