Effects of Preoperative Anxiety and General Anesthetic Administration on Intraoperative Awareness in Patients Undergoing Cesarean Section

• Published in: Haseki tıp bülteni Vol. 57; no. 2; pp. 114 - 121
• Main Authors: Gençoğlu, Nilay Nur, Küçükosman, Gamze, Aydın, Bengü Gülhan, Okyay, Dilek Rahşan, Pişkin, Özcan, Sezer, Üstün, Harma, Mehmet İbrahim, Ayoğlu, Hilal
• Format: Journal Article
• Language: English
• Published: Istanbul Haseki Eğitim ve Araştırma Hastanesi 01.06.2019; Galenos Publishing House; Galenos Yayinevi
• Subjects: Analgesics; Anesthesia; Anesthesiology; Anxiety; awareness; bispectral index; Cesarean section; end-tidal sevoflurane; Health risk assessment; Hypertension; Intubation; isolated forearm; Ketamine; Obstetrics; Pain; Sağlık Hizmetleri; Surgery; Tıp; İstanbul; Türkiye; Turkey; end-tidal sevofluran; izole önkol; cesarean section; bispektral indeks; farkındalık; awareness; isolated forearm; bispectral index; sezaryen seksiyo; Anksiyete; Anxiety; end-tidal sevoflurane
• ISSN: 1302-0072; 2147-2688
• DOI: 10.4274/haseki.galenos.2018.4480

Aim: The aim was to investigate the effects of preoperative anxiety and general anesthetic administrations on intraoperative awareness among patients undergoing cesarean section. Methods: This prospective randomized study included 90 pregnant subjects. Preoperative anxiety was assessed using the Beck Anxiety Inventory. The patients were divided into three groups: group P received propofol 2.5 mg/kg, group T thiopental 5 mg/kg and group K received ketamine 1 mg/kg. Data on intraoperative hemodynamics, isolated forearm (IFA) responses and time to first pain and to first analgesic requirement evaluated using postoperative numerical rating scale were recorded. The Modified Brice Scale (MBS) was used to assess awareness. Results: The preoperative anxiety levels in the groups were low and demographic data were similar (p>0.05). There was no statistically significant difference in IFA response between the groups (p>0.05). Group T had higher MAP at all times and NRS values at hour 0 compared to the other groups (p<0.05), and had shorter time to first analgesic requirement (p<0.05). MBS responses were evaluated as recall in 12 cases in group K, four in group P and three in group T. Conclusion: As the anxiety levels in pregnants were low, the superiority of agents used in induction over each other regarding awareness could not be shown.