Fertility Preservation with Treatment of Immature Teratoma of the Ovary

Fertility preservation for a patient with advanced immature teratoma of the ovary is reported. The patient, a 29-year-old woman, delivered a healthy baby after having had ovarian immature teratoma, grade 3, uncertain stage, at 13 years of age. She was initially treated with unilateral salpingo-oopho...

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Published inJournal of the Chinese Medical Association Vol. 70; no. 5; pp. 218 - 221
Main Authors Chen, Chia-Hui, Yang, Ming-Jie, Cheng, Ming-Huei, Yen, Ming-Shyen, Lai, Chiung-Ru, Wang, Peng-Hui
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.05.2007
Subjects
Adult
Female
Fertility
fertility-preserving surgery
Humans
immature teratoma
Internal Medicine
Ovarian Neoplasms - physiopathology
Ovarian Neoplasms - therapy
ovary
Teratoma - physiopathology
Teratoma - therapy
immature teratoma
ovary
fertility-preserving surgery
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Summary:Fertility preservation for a patient with advanced immature teratoma of the ovary is reported. The patient, a 29-year-old woman, delivered a healthy baby after having had ovarian immature teratoma, grade 3, uncertain stage, at 13 years of age. She was initially treated with unilateral salpingo-oophorectomy and a contralateral wedge resection for tumor invasion, followed by a 6-course cisplatin + vinblastine + bleomycin regimen, a second operation, and an additional 6-course etoposide and cisplatin regimen with complete remission. The patient delivered a healthy baby 16 years after the initial treatment. Based on this successful case, intensive fertility-preserving surgery followed by chemotherapy, even in advanced-stage immature teratomas of the ovary, may be effective in preserving the reproductive function of women with malignant immature teratomas of the ovary.
ISSN:1726-4901
1728-7731
DOI:10.1016/S1726-4901(09)70362-4