Endometrial carcinosarcoma presenting as a tibial metastasis

• Published in: International journal of clinical oncology Vol. 12; no. 4; pp. 305 - 308
• Main Authors: Ishibashi, Masako, Fujiwaki, Ritsuto, Nakayama, Ichiro, Miura, Hiroshi, Sawada, Kohji
• Format: Journal Article
• Language: English
• Published: Japan Springer Nature B.V 01.08.2007
• Subjects: Bone cancer; Bone Neoplasms - pathology; Bone Neoplasms - radiotherapy; Bone Neoplasms - secondary; Carcinosarcoma - pathology; Carcinosarcoma - radiotherapy; Carcinosarcoma - secondary; Endometrial cancer; Endometrial Neoplasms - pathology; Female; Humans; Middle Aged; Oncology; Radiation therapy; Radiography; Tibia - diagnostic imaging; Tibia - pathology
• ISSN: 1341-9625; 1437-7772
• DOI: 10.1007/s10147-006-0652-8

Metastasis to a lower-extremity bone is an extremely rare event in patients with endometrial carcinoma. A 64-year-old woman presented with progressive right leg pain but no gynecologic complaints. A diagnostic workup revealed primary endometrial carcinosarcoma with an isolated tibial metastasis. Though the patient received only local irradiation to the tibial lesion, complete resolution of symptoms resulted. Six months after the radiotherapy, the intraabdominal disease progressed and the patient died. We note that tibial metastasis is one of the possible presenting symptoms in patients with endometrial malignant tumors. Irradiation can improve their quality of life and so may be effective in the management of symptomatic tibial metastasis.