Discrepancy between coronary artery calcium score and HeartScore in middle-aged Danes: the DanRisk study
Coronary artery calcification (CAC) is an independent and incremental risk marker. This marker has previously not been compared to the HeartScore risk model. A random sample of 1825 citizens (men and women, 50 or 60 years of age) was invited for screening. Using the HeartScore model, the 10-year ris...
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Published in | European journal of preventive cardiology Vol. 19; no. 3; p. 558 |
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Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
01.06.2012
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Subjects | |
Online Access | Get more information |
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Summary: | Coronary artery calcification (CAC) is an independent and incremental risk marker. This marker has previously not been compared to the HeartScore risk model.
A random sample of 1825 citizens (men and women, 50 or 60 years of age) was invited for screening.
Using the HeartScore model, the 10-year risk of fatal cardiovascular events based on gender, age, smoking, systolic blood pressure, and total cholesterol was estimated. A low risk was defined as <5%. The CAC score was calculated from a non-contrast enhanced cardiac-CT scan and given in Agatston U.
A total of 1257 (69%) of the invited subjects were interested in the screening. Due to previous cardiovascular disease or diabetes mellitus, 101 were excluded. Of the remaining 1156, 47% were men and 53% women; one half were 50 years old and the other half 60 years old. A low HeartScore was found in 901 of which 334 (37%) had CAC. A high HeartScore was recorded in 251 of which 80 (32%) did not have any CAC. High HeartScores and CAC were significantly more common in males than females.
CAC is common in healthy middle-aged Danes with a low HeartScore, and, on the contrary, high-risk subjects very frequently do not have CAC. The therapeutic and prognostic implications of these observations remain to be clarified. |
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ISSN: | 2047-4881 |
DOI: | 10.1177/1741826711409172 |