Septic arthritis due to Haemophilus influenzae serotype a in the post-vaccination era in Brazil

• Published in: Journal of medical microbiology Vol. 57; no. Pt 10; p. 1311
• Main Authors: de Almeida, Antonio Eugenio Castro Cardoso, Schroeder, Letícia Ferreira Lima, Caldeira, Nathalia Gonçalves Santos, da Silva, Nicéa Magaly Matias, Batista, Paulo Roberto, Gallo, Marta Pradel, de Filippis, Ivano
• Format: Journal Article
• Language: English
• Published: England 01.10.2008
• Subjects: Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - therapeutic use; Arthritis, Infectious - epidemiology; Arthritis, Infectious - microbiology; Arthritis, Infectious - prevention & control; Brazil - epidemiology; Cefuroxime - administration & dosage; Cefuroxime - therapeutic use; Child, Preschool; Female; Haemophilus Infections - epidemiology; Haemophilus Infections - prevention & control; Haemophilus influenzae; Haemophilus Vaccines; Humans; Brazil
• ISSN: 0022-2615; 1473-5644
• DOI: 10.1099/jmm.0.2008/001669-0

Haemophilus influenzae (Hi) is an important bacterial pathogen in children, causing a variety of respiratory infections and life-threatening diseases such as meningitis, epiglottitis, pneumonia and septicaemia. Occasionally, Hi can also cause sporadic infections such as septic arthritis (SA). Before the advent of Hi type b (Hib) vaccination, paediatric invasive Hi disease was caused mostly by Hib isolates. Hib SA in children had been responsible for a significant proportion of cases in Europe and the United States (Bowerman et al., 1997; Peltola et al., 1998; Shoaib et al., 2007).