Synthesis and physicochemical evaluation of a new carrier based on an interpolyelectrolyte complex formed by Eudragit® EPO and Carbomer 940

• Published in: Pharmaceutical chemistry journal Vol. 44; no. 5; pp. 271 - 273
• Main Authors: Mustafin, R. I, Kabanova, T. V, Zhdanova, E. R, Bukhovets, A. V, Garipova, V. R, Nasibullin, Sh. F, Kemenova, V. A
• Format: Journal Article
• Language: English
• Published: Boston Boston : Springer US 01.10.2010; Springer US; Springer
• Subjects: Acrylic acid; Carbomer 940; Drug delivery systems; Drugs; Erythropoietin; Eudragit® EPO; interpolyelectrolyte complexes; Medicine; Organic Chemistry; Pharmacology/Toxicology; Pharmacy; physicochemical properties; Vehicles; interpolyelectrolyte complexes; Carbomer 940; physicochemical properties; EPO; Eudragit

The formation of interpolyelectrolyte complexes (IPEC) between Eudragit® EPO (EPO) and Carbomer 940 (C940) was investigated with a view to their use in peroral controlled-release drug delivery systems. The structure of the synthesized products was investigated using FTIR spectroscopy and MT—DSC meth...