Gender Effect on Clinical Profiles, Pharmacological Treatments and Prognosis in Patients Hospitalized for Heart Failure

Heart failure (HF) is a significant disease affecting 1-2% of the general population. Despite its general aspects, HF, like other cardiovascular diseases, presents various gender-specific aspects in terms of etiology, hemodynamics, clinical characteristics, therapy, and outcomes. As is well known, H...

Full description

Saved in:
Bibliographic Details
Published inJournal of clinical medicine Vol. 13; no. 3; p. 881
Main Authors Fazzini, Luca, Casati, Mattia, Martis, Alessandro, Perra, Ferdinando, Rubiolo, Paolo, Deidda, Martino, Mercuro, Giuseppe, Cadeddu Dessalvi, Christian
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 01.02.2024
Subjects
Cancer therapies
Cardiovascular disease
Demographic aspects
Drug therapy
Females
Gender differences
Heart failure
Prognosis
Womens health
Italy
acute heart failure
pharmacological treatments
prognosis
gender medicine
Online AccessGet full text

Cover

More Information
Summary:Heart failure (HF) is a significant disease affecting 1-2% of the general population. Despite its general aspects, HF, like other cardiovascular diseases, presents various gender-specific aspects in terms of etiology, hemodynamics, clinical characteristics, therapy, and outcomes. As is well known, HF with preserved ejection fraction more frequently affects females, with diabetes and arterial hypertension representing the most critical determinants of HF. On the other hand, women are traditionally underrepresented in clinical trials and are often considered undertreated. However, it is not clear whether such differences reflect cultural behaviors and clinical inertia or if they indicate different clinical profiles and the impact of sex on hard clinical outcomes. We aimed to review the sex-related differences in patients affected by HF.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm13030881