Anti-Aging Effects of Flavonoids from Plant Extracts

• Published in: Foods Vol. 13; no. 15; p. 2441
• Main Authors: Păcularu-Burada, Bogdan, Cîrîc, Alexandru-Ionuț, Begea, Mihaela
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.08.2024
• Subjects: Age related diseases; Aging; anti-aging; Bioactive compounds; Bioavailability; Biological products; Biomarkers; Cardiovascular disease; Care and treatment; Clinical trials; Cocoa; Cosmeceuticals; Cytokines; Diabetes; Diabetes mellitus; Dietary supplements; diseases; Enzymes; Fatty acids; Flavonoids; Food additives; Free radicals; Functional foods; Functional foods & nutraceuticals; Health aspects; Inflammation; Isoflavones; Mitochondrial DNA; Nitrogen; nutraceuticals; Oxidative stress; Phytochemicals; Plant cells; Plant extracts; Senescence; Skin; Tissue engineering; Tumor necrosis factor-TNF; Romania; senescence; diseases; anti-aging; flavonoids; nutraceuticals
• ISSN: 2304-8158; 2304-8158
• DOI: 10.3390/foods13152441

Aging is a natural and irreversible process, affecting living organisms by negatively impacting the tissues' and cells' morphology and functionality and consequently being responsible for aging-related diseases. Taking into account the actual preoccupations of both consumers and researchers, healthy anti-aging alternatives are being intensively studied in order to address such concerns. Due to their functional features, plant flavonoids can be considered valuable nutraceuticals. This paper highlights the possibilities to use flavonoids extracted from various plants for their anti-aging potential on the skin, brain, and heart. Moreover, their anticarcinogenic, anti-inflammatory, and anti-diabetic properties are summarized, along with the senescence-associated mechanisms. Both the nutraceutical and cosmeceutical fields are continuously developing and flavonoids originating from plants are promising candidates to obtain such products. Thus, the bioactive compounds' extraction and their subsequent involvement in innovative product manufacturing must be carefully performed while being aware of the various intrinsic and extrinsic factors that may affect the phytochemicals' structures, bioavailability, and health effects.