The Exclusivity of Multivalency in Dynamic Covalent Processes
Less is more: It is much less efficient to synthesize both components of a multivalent recognition site separately than it is to use one multivalent component to act as a template for the catalytically orchestrated construction of the other component, as demonstrated by the formation of the mechanic...
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Published in | Angewandte Chemie (International ed.) Vol. 43; no. 25; pp. 3273 - 3278 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Weinheim
WILEY-VCH Verlag
21.06.2004
WILEY‐VCH Verlag Wiley |
Subjects | |
Online Access | Get full text |
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Summary: | Less is more: It is much less efficient to synthesize both components of a multivalent recognition site separately than it is to use one multivalent component to act as a template for the catalytically orchestrated construction of the other component, as demonstrated by the formation of the mechanically interlocked, triply threaded molecular bundle shown. The situation is reminiscent of nature. |
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Bibliography: | istex:56A0FE813B65531D23D4AAB914857C72F602E805 ark:/67375/WNG-R0JWQJCW-0 ArticleID:ANIE200453963 We thank the National Science Foundation (CHE 0317170) for funding this research which is also supported in part by equipment grants (CHE 9974928 and CHE 0092036) from the National Science Foundation. We also thank the Office of Naval Research for support through its MURI program. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1433-7851 1521-3773 |
DOI: | 10.1002/anie.200453963 |