Paroxetine treatment of delusional disorder, somatic type

A 77‐year‐old female showed delusion of infestation in the oral cavity. She was treated by paroxetine 20 mg/day, and the hypochondriacal delusion disappeared after 8 weeks. Hypoperfusion in the left temporal and parietal lobes which was observed when she had the delusion was normalized after resolut...

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Published inHuman psychopharmacology Vol. 19; no. 5; pp. 351 - 352
Main Authors Hayashi, Hiroshi, Oshino, Shingo, Ishikawa, Junichi, Kawakatsu, Shinobu, Otani, Koichi
Format Journal Article
LanguageEnglish
Published Chichester, UK John Wiley & Sons, Ltd 01.07.2004
Subjects
Aged
Antidepressive Agents, Second-Generation - administration & dosage
Antidepressive Agents, Second-Generation - therapeutic use
delusional disorder somatic type
Female
Humans
Parietal Lobe - diagnostic imaging
paroxetine
Paroxetine - administration & dosage
Paroxetine - therapeutic use
Schizophrenia, Paranoid - diagnostic imaging
Schizophrenia, Paranoid - drug therapy
serotonin
SPECT
Temporal Lobe - diagnostic imaging
Tomography, Emission-Computed, Single-Photon
Online AccessGet full text
ISSN0885-6222
1099-1077
DOI10.1002/hup.590

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Abstract A 77‐year‐old female showed delusion of infestation in the oral cavity. She was treated by paroxetine 20 mg/day, and the hypochondriacal delusion disappeared after 8 weeks. Hypoperfusion in the left temporal and parietal lobes which was observed when she had the delusion was normalized after resolution of the delusion. This report suggests that paroxetine may be effective for delusional disorder, somatic type. It also supports the previous views that this disorder is associated with serotonergic dysfunction and hypoperfusion in the temporal and parietal lobes. Copyright © 2004 John Wiley & Sons, Ltd.
AbstractList A 77-year-old female showed delusion of infestation in the oral cavity. She was treated by paroxetine 20 mg/day, and the hypochondriacal delusion disappeared after 8 weeks. Hypoperfusion in the left temporal and parietal lobes which was observed when she had the delusion was normalized after resolution of the delusion. This report suggests that paroxetine may be effective for delusional disorder, somatic type. It also supports the previous views that this disorder is associated with serotonergic dysfunction and hypoperfusion in the temporal and parietal lobes.
A 77‐year‐old female showed delusion of infestation in the oral cavity. She was treated by paroxetine 20 mg/day, and the hypochondriacal delusion disappeared after 8 weeks. Hypoperfusion in the left temporal and parietal lobes which was observed when she had the delusion was normalized after resolution of the delusion. This report suggests that paroxetine may be effective for delusional disorder, somatic type. It also supports the previous views that this disorder is associated with serotonergic dysfunction and hypoperfusion in the temporal and parietal lobes. Copyright © 2004 John Wiley & Sons, Ltd.
A 77-year-old female showed delusion of infestation in the oral cavity. She was treated by paroxetine 20 mg/day, and the hypochondriacal delusion disappeared after 8 weeks. Hypoperfusion in the left temporal and parietal lobes which was observed when she had the delusion was normalized after resolution of the delusion. This report suggests that paroxetine may be effective for delusional disorder, somatic type. It also supports the previous views that this disorder is associated with serotonergic dysfunction and hypoperfusion in the temporal and parietal lobes.A 77-year-old female showed delusion of infestation in the oral cavity. She was treated by paroxetine 20 mg/day, and the hypochondriacal delusion disappeared after 8 weeks. Hypoperfusion in the left temporal and parietal lobes which was observed when she had the delusion was normalized after resolution of the delusion. This report suggests that paroxetine may be effective for delusional disorder, somatic type. It also supports the previous views that this disorder is associated with serotonergic dysfunction and hypoperfusion in the temporal and parietal lobes.
Author Otani, Koichi
Ishikawa, Junichi
Oshino, Shingo
Kawakatsu, Shinobu
Hayashi, Hiroshi
Author_xml – sequence: 1
  givenname: Hiroshi
  surname: Hayashi
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  givenname: Shingo
  surname: Oshino
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  givenname: Junichi
  surname: Ishikawa
  fullname: Ishikawa, Junichi
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  givenname: Shinobu
  surname: Kawakatsu
  fullname: Kawakatsu, Shinobu
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  givenname: Koichi
  surname: Otani
  fullname: Otani, Koichi
  email: otani@med.icl.yamagata‐u.ac.jp
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A 77-year-old female showed delusion of infestation in the oral cavity. She was treated by paroxetine 20 mg/day, and the hypochondriacal delusion disappeared...
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SubjectTerms Aged
Antidepressive Agents, Second-Generation - administration & dosage
Antidepressive Agents, Second-Generation - therapeutic use
delusional disorder somatic type
Female
Humans
Parietal Lobe - diagnostic imaging
paroxetine
Paroxetine - administration & dosage
Paroxetine - therapeutic use
Schizophrenia, Paranoid - diagnostic imaging
Schizophrenia, Paranoid - drug therapy
serotonin
SPECT
Temporal Lobe - diagnostic imaging
Tomography, Emission-Computed, Single-Photon
Title Paroxetine treatment of delusional disorder, somatic type
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fhup.590
https://www.ncbi.nlm.nih.gov/pubmed/15252828
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