Thrombolytic therapy in an adolescent ischemic stroke

We report the case of a 16-year-old Caucasian girl who developed acute onset of left hemiplegia, left hemisensory deficit, and dysarthria. After a negative computed tomographic scan of the brain, the patient was given intravenous recombinant tissue plasminogen activator according to established adul...

Full description

Saved in:
Bibliographic Details
Published inJournal of child neurology Vol. 16; no. 4; p. 286
Main Authors Noser, E A, Felberg, R A, Alexandrov, A V
Format Journal Article
LanguageEnglish
Published United States 01.04.2001
Subjects
Adolescent
Brain Ischemia - drug therapy
Female
Fibrinolytic Agents - administration & dosage
Fibrinolytic Agents - pharmacology
Humans
Infusions, Intravenous
Stroke - drug therapy
Tissue Plasminogen Activator - administration & dosage
Tissue Plasminogen Activator - pharmacology
Treatment Outcome
Venous Thrombosis
Online AccessGet more information

Cover

More Information
Summary:We report the case of a 16-year-old Caucasian girl who developed acute onset of left hemiplegia, left hemisensory deficit, and dysarthria. After a negative computed tomographic scan of the brain, the patient was given intravenous recombinant tissue plasminogen activator according to established adult guidelines. The patient experienced a marked improvement within 24 hours. Stroke etiology was determined to be a paradoxical embolus via a patent foramen ovale associated with pelvic vein thrombosis. This case illustrates the importance of early recognition of stroke and the utility of thrombolytics in treating ischemic infarcts in the adolescent population.
ISSN:0883-0738
DOI:10.1177/088307380101600410