An interview with Mario Polo

[...]LRS is likely doomed to fail, as the condition tends to recur in a significant number of individuals. [...]you might get a 40-60 year old individual in which you might have to use a lower dose than what you could be using with a younger individual: you choose your dose based on the amount of gi...

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Bibliographic Details
Published inDental press journal of orthodontics Vol. 22; no. 6; pp. 14 - 24
Main Author Polo, Mario
Format Journal Article
LanguageEnglish
Published Brazil Dental Press International 01.11.2017
Dental Press Editora
Subjects
Associations
Awards & honors
Botulinum toxin
Dentistry
Hispanic or Latino
History, 20th Century
History, 21st Century
Interview
Orthodontics
Orthodontics - history
Polo
Texas
Texas
United States > US
Puerto Rico
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Summary:[...]LRS is likely doomed to fail, as the condition tends to recur in a significant number of individuals. [...]you might get a 40-60 year old individual in which you might have to use a lower dose than what you could be using with a younger individual: you choose your dose based on the amount of gingiva exposed, dictated by the amount of contraction and elevation of the upper lip musculature, NOT by the age of the patient. A mean of 240 U of Abobotulinumtoxin A (Ipsen Biopharm Ltd., Werexham, UK), another commercially available product similar to Botox (Onabotulinumtoxin A, Allergan, CA, USA) were injected in both masseter muscles of 121 individuals over a 4.28 year-period, 5-8 sessions every 6 months, and muscle mass thickness was measured with ultrasound technology. Since there is a dose variation between these two botulinum-A toxins, it is worth stating that 240 Abo Units are equivalent to roughly 100 Ona Units. Besides anatomy, in order to familiarize yourself with neurotoxins, read anything you can find in the literature related to BTX-A’s mode of action, physiology, myophysiology, pharmacology, immunology, and pathology.
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Flavia Artese: » Adjunct Professor in Orthodontics, Universidade Estadual do Rio de Janeiro (UERJ, Brazil). » Diplomate of the Brazilian Board of Orthodontics and Facial Orthopedics (BBO, Brazil). » Associate Editor of the Dental Press Journal of Orthodontics and Journal of the World Federation of Orthodontists. » President of the Associação Brasileira de Ortodontia (ABOR, Brazil).
Nelson Mucha: » Dental Degree, Universidade de Passo Fundo (UPF, Brazil). » Specialist in Dental Prosthesis, Universidade de Campinas (UNICAMP, Brazil). » MSc and PhD in Orthodontics, Universidade Federal do Rio de Janeiro (UFRJ, Brazil). » Full Professor in Orthodontics, Universidade Federal Fluminense (UFF, Brazil). » Visitor Professor at Saint Louis University (USA). » Founder and former President of the Brazilian Board of Orthodontics and Facial Orthopedics (BBO, Brazil).
Mayra Seixas: » Dental Degree, Universidade Federal da Bahia (UFBA, Brazil). » MSc in Orthodontics, Universidade Federal do Rio de Janeiro (UFRJ, Brazil). » Diplomate of the Brazilian Board of Orthodontics and Facial Orthopedics (BBO, Brazil).
Víctor L. Acevedo Rivera: » DMD (Cum Laude) School of Dentistry, University of Puerto Rico Medical Sciences Campus (Puerto Rico). » MSc in Orthodontics, School of Dentistry, University of Michigan (USA). » Diplomate of the American Board of Orthodontics .
ISSN:2176-9451
2177-6709
2177-6709
DOI:10.1590/2177-6709.22.6.014-024.int