Palladium-loaded ceramic membrane-catalyzed flow-through Suzuki-Miyaura reaction

A general Pd-loaded ceramic membrane catalyzed Suzuki-Miyaura reaction in a flow-through membrane reactor is reported for the first time. Versatile (hetero)aryl bromides and chlorides proceeded well with an array of (hetero)aryl boronic acids. The consistently high activity of the catalytic membrane...

Full description

Saved in:
Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 59; no. 43; pp. 6568 - 6571
Main Authors Wang, Shuangqiang, Chen, Jinliang, Zhang, Fei, Zhao, Yao, Wu, Xiaojin, Chen, Rizhi
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 25.05.2023
Royal Society of Chemistry
Subjects
Aromatic compounds
Bromides
Chemical reactions
Chemical synthesis
Chemistry
Chemistry, Multidisciplinary
Coupling (molecular)
Cross coupling
Membranes
Palladium
Physical Sciences
Recyclability
Science & Technology
NANOPARTICLES
FABRICATION
HYDROGENATION
CROSS-COUPLING REACTION
PERFORMANCE
Online AccessGet full text

Cover

More Information
Summary:A general Pd-loaded ceramic membrane catalyzed Suzuki-Miyaura reaction in a flow-through membrane reactor is reported for the first time. Versatile (hetero)aryl bromides and chlorides proceeded well with an array of (hetero)aryl boronic acids. The consistently high activity of the catalytic membrane in eight cycles has proved its good stability and recyclability. Synthesis of drug molecules has further demonstrated that the catalytic membrane protocol is a powerful and comprehensive alternative to the traditional Suzuki-Miyaura cross-coupling. A general Suzuki-Miyaura reaction catalyzed by a Pd-loaded ceramic membrane in a flow-through membrane reactor is reported for the first time.
Bibliography:Electronic supplementary information (ESI) available. See DOI
https://doi.org/10.1039/d3cc01518a
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1359-7345
1364-548X
DOI:10.1039/d3cc01518a