Red and near infrared persistent luminescence nano-probes for bioimaging and targeting applications
The introductory aspect of this review starts with a prologue on bioimaging in general and optical imaging in particular, and finally focuses on the most recently explored red and near infrared (NIR) emitting persistent luminescence nanoparticles (PLNPs) for bioimaging applications. Accordingly, a p...
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| Published in | RSC advances Vol. 4; no. 12; pp. 58674 - 58698 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
01.01.2014
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| Subjects | |
| Online Access | Get full text |
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| Summary: | The introductory aspect of this review starts with a prologue on bioimaging in general and optical imaging in particular, and finally focuses on the most recently explored red and near infrared (NIR) emitting persistent luminescence nanoparticles (PLNPs) for bioimaging applications. Accordingly, a pre-requisite towards a better understanding of the subject makes it vital to talk about persistent luminescence, and the developments in red and NIR emitting persistent phosphors. In this context, different synthesis techniques to design nanoparticles and chemically modified (surface modification) nanostructures have also been summarized. Finally, the use of these nanostructures as bioimaging and targeting probes, both for
in vitro
and
in vivo
studies, in diverse frameworks, has been reviewed in detail. The significant findings suggest that, Mn
2+
and/or Cr
3+
doped nanostructures, particularly gallogermanates, are able to give an intense red-near infrared persistent emission with a longer afterglow time for more than 2 weeks and are suitable for bio-imaging applications. The review also talks about the remaining challenges, new dimensions and future course of research in this field.
Schematic representation of the different processes in persistent luminescence: charging (1), stimulation (2), discharging (3) (PET-persistent energy transfer, QT-quantum tunneling). |
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| Bibliography: | Sunil K Singh, born in 1982, received his doctoral degree in Physics in 2011 from the Banaras Hindu University, India. Currently, he is a DST-INSPIRE faculty at the Indian Institute of Technology (Banaras Hindu University), Varanasi, India. His research interest includes the physics of multimodal luminescence (upconversion, downconversion/quantum-cutting, downshifting), including persistent luminescence in lanthanide and transition metal doped nanostructures. In terms of applications, the focus is on bio-imaging, to increase the conversion efficiency of photovoltaic cells, sensors, and for security purposes. He has authored/co-authored a book chapter, a review article and more than 30 peer-reviewed journal articles, and his current h-index is 11 (Sep. 2014). ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 2046-2069 2046-2069 |
| DOI: | 10.1039/c4ra08847f |