A Study of Three Cases of Familial Related Agenesis of the Corpus Callosum

This paper provides data on a family in which three members, all female, have been diagnosed as having agenesis of the corpus callosum. That all three acallosal individuals came from the same family and showed relatively uniform neuropsychological impairment and could be compared in similar terms wi...

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Bibliographic Details
Published inJournal of clinical and experimental neuropsychology Vol. 22; no. 6; pp. 731 - 742
Main Authors Finlay, D.C., Peto, T., Payling, J., Hunter, M., Fulham, W.R., Wilkinson, I.
Format Journal Article
LanguageEnglish
Published Colchester Taylor & Francis Group 01.12.2000
Taylor & Francis
Subjects
Adolescent
Adult
Adult and adolescent clinical studies
Agenesis of Corpus Callosum
Biological and medical sciences
Brain Diseases - congenital
Brain Diseases - genetics
Brain Diseases - pathology
Child
Corpus Callosum - pathology
Female
Functional Laterality
Humans
Intelligence
Learning
Medical sciences
Neuropsychological Tests
Organic mental disorders. Neuropsychology
Psychology. Psychoanalysis. Psychiatry
Psychometrics
Psychomotor Performance
Psychopathology. Psychiatry
Reading
Human
Memory disorder
Nervous system diseases
Agenesis
Cognitive disorder
Family study
Non verbal intelligence
Corpus callosum
Cerebral disorder
Malformation
Central nervous system disease
Female
Verbal intelligence
Intellectual ability
Interhemispheric transfer
Intelligence quotient
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Summary:This paper provides data on a family in which three members, all female, have been diagnosed as having agenesis of the corpus callosum. That all three acallosal individuals came from the same family and showed relatively uniform neuropsychological impairment and could be compared in similar terms with their "callosal" siblings, also female, provides a unique sample. Inter-hemispheric transfer, psychometric measures, and motor and cognitive function were examined in the acallosal individuals, all of whom had borderline to low-average intelligence, with results compared to their non-acallosal siblings. The data indicated that all acallosal individuals exhibited deficits with the cognitive tests indicating difficulties of inter-hemispheric transfer of tactile information, difficulties in some areas of memory and, at least as far as the children are concerned, a marked difference in Verbal IQ and Performance IQ.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:1380-3395
1744-411X
DOI:10.1076/jcen.22.6.731.962